This review highlights progress in plant biotin research by focusing on the four major areas of recent investigation: the structure, enzymology, and localization of two important biotinylated proteins (methylcrotonoyl-CoA carboxylase involved in...Claude Alban...
Amino-acid sequences of three functional units from various biotin-dependent carboxylases, biotin carboxylase, biotin-carboxyl-carrier protein and carboxyl transferase, were investigated by computer-assisted sequence comparison to obtain information about the structure, function, and molecular evolution of ...
Amino-acid sequences of three functional units from various biotin-dependent carboxylases, biotin carboxylase, biotin-carboxyl-carrier protein and carboxyl transferase, were investigated by computer-assisted sequence comparison to obtain information about the structure, function, and molecular evolution of th...
The enzyme holocarboxylase synthetase (HCS) transforms biotin into its active form 5′-biotinyl-AMP and this compound is used to biotinylate five biotin-dependent carboxylases or to activate a soluble guanylate cyclase (sGC) and a cGMP-dependent protein kinase (PKG). The HCS–sGC–PKG pathway ...
They contained large amounts of a small biotin-carrying protein, which is most likely part of the acetyl-CoA and propionyl-CoA carboxylases. Other ... C Menendez,Z Bauer,H Huber,... - 《Journal of Bacteriology》 被引量: 266发表: 1999年 The short-term regulation of hepatic acetyl-CoA ...
Aureus Carboxyltransferases Yeast Carboxyltransferase and the α-Subunit of Glutaconyl-CoA Decarboxylase Transcarboxylase 12S Subunit and the β-Subunit of Propionyl-CoA Carboxylase Active Site Architecture and Substrate Binding Inhibitors of Carboxyltransferase Carboxyltransferase Domains without a Crotonase ...
Inmammalian cells, holocarboxylase synthetase, or HLCS, is the enzyme that serves to distribute biotin to the biotin-dependent proteins. Gene silencing of HLCS mitigates the glioblastoma's tumorigenicity—its tendency to develop tumors—in mouse models. High HLCS expression is also associated with gl...
55Citations 17Altmetric Metrics Abstract Proximity dependent biotin identification (BioID) has emerged as a powerful tool for studies of proteome architecture, including insoluble or membrane-associated proteins. The technique has been well established in mammalian cells but has yet to be applied to wh...
Tong L. 2013. Structure and function of biotin-dependent carboxylases. Cell Mol Life Sci 70:863-891.Tong, L. Structure and function of biotin-dependent carboxylases. Cell. Mol. Life Sci. 70, 863-891 (2013).Tong L. Structure and function of biotin-dependent carboxylases. Cell Mol Life ...
(1993). Molecular evolution of biotin-dependent carboxylases. Eur J Biochem 215, 687-696.Toh et al., " Molecular Evolution Of Biotin-Dependent Carboxylases, " Eur. J. Biochem., 215:687-696, 1993.Toh H, Kondo H, Tanabe T (1993) Molecular evolution of biotin-dependent carboxylases. Eur...