Biotin interferences are noted in immunoassays of thyroid markers, drugs, hormones, cancer markers, the biomarker for cardiac function (β-human chorionic gonadotropin), etc. The biotin level required for serious interference in test results varies significantly from test to test and cannot easily be...
Chapter 7-Issues of Interference in Drugs of Abuse Testing and Toxicology Pages 113-132 Purchase View chapter Select Index Book chapterFull text access Index Pages 133-136 View PDF View chapter About the book Description Biotin and Other Interferences in Immunoassays: A Concise Guideis aimed at cl...
Some of the most frequently noted biotin interferences are with immunoassays for thyroid markers, high-sensitivity cardiac troponin, and N-terminal pro-brain natriuretic peptide. For troponins, the interference portrays a falsely lower value for these markers and disrupts its predictive value of cardiac...
Most of the published research on biotin interference covers hormone tests, such asparathyroid hormone (PTH),thyroid stimulating hormone (TSH),T4andT3tests, as well as tests for troponin. However, because biotin is used in so many immunoassays, scientists say it could interfere with many others....
Vitamin and mineral status in physically active men: effects of a high-potency supplement. Am J Clin Nutr. 1992;55(1):1-7.PubMedGoogle Scholar 30. Wijeratne NG, Doery JCG, Lu ZX. Positive and negative interference in immunoassays following biotin ingestion: a pharmacokinetic study. ...
RNA interference (RNAi) is a process by which short interfering RNAs (siRNAs) direct the degradation of complementary single-strand RNAs. In this study, we... KRAYNACK,A B. - 《Rna-a Publication of the Rna Society》 被引量: 204发表: 2006年 加载更多研究点推荐 (+) biotin ...
Immunoassays for human urinary cotinine [(S)-()-cotinine], a major nicotine metabolite, are useful to monitor the degree of tobacco smoke exposure. However... N Kobayashi,E Banzono,Y Shimoda,... - 《Analytical Methods》 被引量: 21发表: 2011年 Vitamin Requirements of the Silkworm In this...
In situhybridization detection (ISH) Enzyme immunoassays (ELISAs) Neuronal tracing Use the VECTASTAIN ABC system if you are looking for: High sensitivity with low background — due to the form and number of active enzyme molecules associated with the avidin/biotinylated enzyme complex ...
"The literature is lacking with regard to biotin interference with serum cortisol and testosterone immunoassays, as in our case-report," Styner said. "Patients are ingesting supplements in a higher frequency, and higher doses, and therefore this case is timely and relevant from both a clinical ...
interferencestreptavidinBackground Reports of false laboratory findings due to a biotin supplementation have raised concerns about the safety of immunoassays. According to current research, biotin is known to cause interference in immunoassays. Since up to 70% of medical decisions are based on laboratory...