InterferenceCompetitive immunoassaySandwich immunoassayThyroid function testsTroponinCertain immunoassays used in clinical laboratories utilized biotin-streptavidin interaction in assay design. These assays utilize biotinylated antibodies and if biotin is present in high concentration in the specimen, it may ...
Chapter 1-Immunoassay Design and Mechanism of Biotin Interference Pages 1-15 Purchase View chapter Select Chapter 2 - Biotin: Pharmacology, Pathophysiology, and Assessment of Biotin Status Book chapterAbstract only Chapter 2-Biotin:Pharmacology, Pathophysiology, and Assessment of Biotin Status ...
Most of the published research on biotin interference covers hormone tests, such asparathyroid hormone (PTH),thyroid stimulating hormone (TSH),T4andT3tests, as well as tests for troponin. However, because biotin is used in so many immunoassays, scientists say it could interfere with many others....
Interference by biotin therapy on measurement of TSH and FT4 by enzyme immunoassay on Boehringer Mannheim ES700 analyser. Ann Clin Biochem. 1996;33(pt 2):162-163.PubMedGoogle ScholarCrossref 33. Kwok JS-S, Chan IH-S, Chan MH-M. Biotin interference on TSH and free thyroid hormone ...
A biotin-drug extraction and acid dissociation (BEAD) procedure to eliminate matrix and drug interference in a protein complex anti-drug antibody (ADA) iso... A biotin-drug extraction and acid dissociation (BEAD) procedure to eliminate matrix and drug interference in a protein complex anti-drug ...
VECTASTAIN®ABC-AP (alkaline phosphatase) Kits provide high sensitivity avidin-biotin based detection in immunohistochemistry (IHC), immunocytochemistry (ICC), protein and nucleic acid blot, in situ hybridization (ISH), and enzyme immunoassay (ELISA) detection. The VECTASTAIN®ABC-AP Kits are ideall...
immunoassayinterferencestreptavidinBackground Reports of false laboratory findings due to a biotin supplementation have raised concerns about the safety of immunoassays. According to current research, biotin is known to cause interference in immunoassays. Since up to 70% of medical decisions are based on...
ClericoAldoPlebaniMario.Clinical Chemistry & Laboratory MedicineClerico A, Plebani M. Biotin interference on immunoassay meth- ods: sporadic cases or hidden epidemic? Clin Chem Lab Med 2017;55:777-9.
Biotin interference: evaluation of an updated thyroglobulin electrochemiluminescent immunoassay.doi:10.1515/cclm-2021-0969biotinECLIAimmunoassaymethod evaluationthyroglobulinhttps://orcid.org/0000-0003-2114-1403EvenepoelAntonSchiettecatteJohanVan DalemAnnelienAnckaertEllenellen.anckaert@uzbrussel.beDepartment of...
Immunoassay interference secondary to therapeutic high‐dose biotin: A paediatric case reportACIDOSISLEVOTHYROXINEMITOCHONDRIAL pathologyDISEASE risk factorsTHERAPEUTICSBackground: Lately, high dose of biotin is often given orally to patients with a primary progressive multiple sclerosis (PPMS). However, the ...