chemistry, and mathematics, as well as courses focused on biotechnology principles and techniques. You may also have the opportunity to participate in laboratory research projects and internships to gain hands-on experience.
The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19) has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical trials of mRNA therapeutics include studies of paracrine vascular endothelia
U2OS cells were plated in a 12-well plate in DMEM medium supplemented with 10% FBS. After 18 h incubation, cells were treated for 6 h with doxorubicin (1 µM), Dox-btn1 (1 µM), Dox-btn2 (1 µM) and 0.1% DMSO (control), respectively, in fresh medium. Then ce...
[Biotechnology and Bioprocessing] Process Validation in Manufacturing of Biopharmaceuticals, Third Edition Volume 20123060 || Commentary on the US Food and Drug Administration’s 2011 “Guidance for Industry, Process Validation General Principles and Pra ...
The inability to rationalise this discrepancy underscores our limited understanding of the regulatory principles which govern the synthesis and excretion of H. jecorina's cellulases. In this review, we summarise the current state of knowl- edge about the mechanisms involved in this regulation, and ...
Sequencing reactions, like PCR, rely on the basic principles of DNA replication and require primers to initiate DNA replication. However, sequencing is performed in just one direction, so instead of a primer pair, sequencing makes use of a single primer per reaction. To get stronger sequence ...
Knowledge of both ash level and composition are prerequisites for effective industrial biomass process design [12, 13], but these parameters are difficult to determine. As a consequence, the diversity of chemical components and their varied proportions among lignocellulosic feedstocks frequently leads to...
Some regulatory bodies in countries outside the EU followed suit and are using the principles of the EMA legal framework. Others, such as the US FDA, introduced a different system. At present, 17 biosimilars have been approved in the USA, but their actual market launch is delayed because of...
Third, many multi-omics data integration algorithms and software programs have been developed on the basis of different statistical principles and assumptions42,43,44. Each multi-omics integration method can report a solution, but assessing its reliability is difficult owing to the lack of multi-...
We developed a collagen-based corneal stromal substitute, BPCDX. BPCDX was manufactured following principles of good manufacturing practices (GMP), in a Class 5 (according to ISO-14644-1) air quality laminar flow clean-room facility in Linköping, Sweden by LinkoCare Life Sciences AB. Although...