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Exploiting sequence–structure–function relationships in biotechnology requires improved methods for aligning proteins that have low sequence similarity to previously annotated proteins. We develop two deep learning methods to address this gap, TM-Vec a
Single nucleotide polymorphisms (SNPs) in metagenomics are used to quantify population structure, track strains and identify genetic determinants of microbial phenotypes. However, existing alignment-based approaches for metagenomic SNP detection require
A simple definition is that a gene is a sequence of nucleotides that specifies the sequence of an RNA or protein. A more complicated definition is that a gene is a physical and functional unit of heredity, which carries information from one generation to the next. In molecular terms, it is...
The reliance on a solitary linear reference genome has imposed a significant constraint on our comprehensive understanding of genetic variation in animals. This constraint is particularly pronounced for non-reference sequences (NRSs), which have not been
1993. 拢8.95 ISBN ()-19-963349-5 (pbk) This book is small in size but great in explaining simple topological terms like linking number, twist, writhe, supercoiled structures, knots, catenanes and topoisomerases. DNA Topology includes references, index, list of abbreviations and a glossary. It...
As stories about GM crops in developing countries unfold, I continue to be struck by how very different each case is. Despite the desire for simple global narratives of success or failure, the crops differ, the transgenic traits differ, the problems to be solved differ, the cultures differ, ...
PubMed Journal articles for Critical reviews in biotechnology were found in PRIME PubMed. Download Prime PubMed App to iPhone, iPad, or Android
Optimizing speed breeding and seed/pod chip based genotyping techniques in pigeonpea: A way forward for high throughput line development Prakash I. Gangashetty Shruthi H. Belliappa Manish K. Pandey Plant Methods(2024) Exploring genetic variability under extended photoperiod in lentil (Lens Culinaris ...
The relationship between proportional abundance of archaea and methane emissions is not simple. Most archaeal strains were present at similar abundance in LME and HME sheep (Supplementary Data 8). RUGs representing new strains of Methanobrevibacter were often more abundant in HME sheep. The RUG with...