higher-level mathematical and computational concepts; (ii) availability of texts that can give a flavor of how contemporary biological problems are approached with quantitative methods; (iii) expectations to cover specific mathematical (or biological) content rather than teach a problem-solving approach....
new invention, a combination of fluorescence and polarization imaging of tissue, provides the information of chemical composition and morphology of tissues. It solves the problem to distinguish flat and early lesions from surrounding normal tissues. ...
Untargeted metabolomics experiments rely on spectral libraries for structure annotation, but, typically, only a small fraction of spectra can be matched. Previous in silico methods search in structure databases but cannot distinguish between correct and incorrect annotations. Here we introduce the COSMIC ...
Our method provides an approach for studying cell fate decisions in complex tissues and development.Similar content being viewed by others Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis Article Open access 06 July 2023 A single-cell time-lapse of mouse ...
Biotechnology is an exemplar of the new forms of knowledge production based on multidisciplinary approaches and problem solving in the context of application. The development of biotechnology, as a form of knowledge production, is characterised by the convergence of a diverse set of skills from a ...
as well as technological subjects that are still in the proof-of-concept stage. Applied Biochemistryand Biotechnologyprovides a forum for case studies and practical concepts of biotechnology, utilization, including controls, statistical data analysis, problem descriptions unique to a particular application,...
Michener CD, Sokal RR (1957) A quantitative approach to a problem in classification. Evolution 11:130–162. https://doi.org/10.1111/j.1558-5646.1957.tb02884.x Article Google Scholar Miyamoto RY, de Melo RR, de Mesquita Sampaio IL, de Sousa AS, Morais ER, Sargo CR, Zanphorlin LM (...
However, the skills shortage in relation to SET entrepreneurship is still considered a key economic problem in the UK (NAO, 2018), as crowded scientific curricula still tend not to incorporate entrepreneurship education as a core component. Consequentially, we argue, there is a need to identify ...
Another approach to earn the multiplicity and smallness of samples is the beads-based one [17] and the essence of it has been successfully adopted in the machine of giga-base (next-generation) sequencers [18]. However, in this approach, there is a difficult problem to cope with: multi-...
As part of a biodiversity conservation strategy, creating bioreservoirs of somatic and stem cell lines through cryogenic preservation can provide a reliable and feasible approach applied to regenerate or restore the biocenotic sustainability among herds of livestock breeds followed by reintroduction of van...