Problem-based learningThis manuscript describes a pilot study in ethics education employing a problem-based learning approach to the study of novel, complex, ethically fraught, unavoidably public, and unavoidably divisive policy problems, called "fractious problems," in bioscience and biotechnology. ...
One such approach, involves the addition of microbial components (pathogen-associated molecular patterns; PAMPs), that can stimulate strong immune responses, into subunit vaccine formulations. The conjugation of PAMPs to subunit antigens provides a means to greatly increase vaccine potency, by targeting...
a, Problem formulation: given unperturbed gene expression (green) and applied perturbation (red), predict the gene expression outcome (purple). Each box corresponds to an individual gene. Arrows indicate change in expression. b, GEARS model architecture. (i) For each gene in the unperturbed state...
Growth kinetics of microorganisms processes involves a parameter estimation problem, which is usually solved by using simulation techniques. A different approach is presented. It is based on a trust-region algorithm for nonlinear least squares problems with bound constraints. The global convergence propert...
Michener CD, Sokal RR (1957) A quantitative approach to a problem in classification. Evolution 11:130–162. https://doi.org/10.1111/j.1558-5646.1957.tb02884.x Article Google Scholar Miyamoto RY, de Melo RR, de Mesquita Sampaio IL, de Sousa AS, Morais ER, Sargo CR, Zanphorlin LM (...
Our method provides an approach for studying cell fate decisions in complex tissues and development.Similar content being viewed by others Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis Article Open access 06 July 2023 A single-cell time-lapse of mouse ...
The evolution of US pollution prevention, 1976–2001: a unique chemical engineering contribution to the environment – a review The importance of pollution prevention or cleaner production has been substantial in changing the environmental approach within advanced industrialized cou... M Overcash - 《Jo...
This approach involves some simple market analysis followed by economic modelling of the whole production process. It also permits an evaluation of which steps in the production process have the greatest effect on the final production cost of the alga or algal product, thus providing a guide as ...
The second fundamental problem with the precautionary principle is that it is based on the unsubstantiated premise that the current regulatory system is insufficiently protective. The current system already tends to err on the side of the safety, as it should, but the relevant question is just ...
whereas the MS1 modification addresses a problem arising from differences between the prokaryotic and eukaryotic expression systems. We also present evidence that MS2 modifications contribute to both aspects. It is interesting that our empirical approach to derive an optimized gRNA was in line with recen...