Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus. Frontiers of Medicine 8:285-93. doi:10.1007/s11684-014-0350-2Zhu X, Zeng X, Sun C, Chen S. Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus. Front Med. 2014; 8: 285-293. https://doi.org/...
Catharanthus roseus is one of the most extensively investigated medicinal plants, which can produce more than 130 alkaloids, including the powerful antitumor drugs vinblastine and vincristine. Here we review the recent advances in the biosynthetic pathway of terpenoid indole alkaloids (TIAs) in C. rose...
Hyoscyamine and scopolamine (HS), two valuable tropane alkaloids of significant medicinal importance, are found in multiple distantly related lineages within the Solanaceae family. Here we sequence the genomes of three representative species that produce HS from these lineages, and one species that does...
(2015) Elucidation of the concise biosynthetic pathway of the communesin indole alkaloids. Angew Chem Int Ed Engl. 127, 3047-3050.Lin H-C, Chiou G, Chooi Y-H, McMahon TC, Xu W, Garg NK, et al. Elucidation of the Concise Biosyn- thetic Pathway of the Communesin Indole Alkaloids. Angew...
Tomato is the highest value fruit and vegetable crop worldwide, yet produces α-tomatine, a renowned toxic and bitter-tasting anti-nutritional steroidal glycoalkaloid (SGA) involved in plant defense. A suite of modifications during tomato fruit maturatio
BMC Bioinformatics (2019) 20:380 https://doi.org/10.1186/s12859-019-2963-6 RESEARCH ARTICLE Open Access Classification of alkaloids according to the starting substances of their biosynthetic pathways using graph convolutional neural networks Ryohei Eguchi1,2, Naoaki Ono1,2* , Aki Hirai Morita1,...
更详细... 英文: Molecular Biology of the Biosynthetic Pathways of Taxol Precursors and Metabolic Engineering of Anti-Tumor Terpenoid Indole Alkaloids 中文: 紫杉醇前体生物合成的分子生物学和抗癌萜类吲哚生物碱的代谢工程更详细...
6) metabolic pathway 代谢途径 1. Studies on metabolic pathway of rice (Oryza sativa L.) allelochemicals and their gene regulation; 水稻化感物质的代谢途径及基因调控 2. Application of Pathway Hunter Tool in metabolic pathway analysising; Pathway Hunter Tool在代谢途径分析中的应用 3. Advance in...
The benzylisoquinolines comprise the largest group of alkaloids with about 2000 structures some of which possess valuable medicinal importance (such as codeine or morphine). During the past years the biosynthetic pathway leading to one group of these alkaloids, namely the protoberberines, was elucidate...
Structural diversity of BIA alkaloids in the leaf is attributed to enzymatic modifications, including intramolecular C–C phenol coupling on ring A and methylation and demethylation at certain positions. Additionally, most BIA biosynthetic pathway genes show higher levels of expression in the leaf of ...