PSA, biopsy Gleason sum, and percentage of cores positive were the three most significant independent predictors of pathologic stage. The assigned percentage of biopsy core-positive subgroups along with pretreatment PSA and highest Gleason sum were used to develop probability nomograms for pathologic ...
Cancer, he said. The biopsy was positive.Cancer, he said. The biopsy was positive.An interview with entrepreneur Sands Bellizi is presented. She recalls the time she got a call from her doctor saying that she has non-Hodgkin's lymphoma, with a cancerous lymph node in her neck and a bi...
Liquid biopsyis a broad term that refers to the analysis of tumor-derived biomarkers isolated from biological fluids of cancer patients (Fig. 1). Although peripheral blood is the main font for liquid biopsy testing, tumor biomarkers can be identified in a variety of body fluids including urine ...
NGS assays are also approved as companion diagnostics to identifyEGFRmutations andALKrearrangements that predict benefits from EGFR-TKIs and ALK-TKIs, respectively. However, the most appealing application of NGS in liquid biopsy is the study of additional druggable alterations (Fig.3). The first stud...
In one group, patients underwent an EB between days 17 and 22 of the menstrual cycle that precedes the ovarian stimulation. In the other group (control), no EB was performed. The hCG-positive rate (early pregnancy rate) was evaluated on day 14 after the ovarian puncture. In total, 157 ...
This problem is partially alleviated in this paper, where we have developed optimized biopsy procedures that could differentiate between prostate specimens having high and low GS/CV by sampling the spatial cancer distributions at the macro level. Differentiation rates of 81.93% (for GS) and 94.79% ...
Conclusion: These data demonstrate that long-term, disease-free (other than re-biopsy) survival is common following a “positive” post-irradiation biopsy without intervention especially among patients with a normal digital rectal exam. Therefore, routine rebiopsy without clinical indications is not a...
77.8% for PET/CT, p = 0.067). The diagnostic parameters of these imaging methods in determining ALN status were demonstrated in Table 2. For patients with N1mi, the sensitivity of PET/CT was 30%, while that of MRI was 60%. Nevertheless, this difference was not statistically ...
The rate of ALK protein immunohistochemical detection was 87.2%, and the rate of coarse needle biopsy detection was higher than that of the fine needle (91 and 72%, P<0.01), but the positive rate between coarse needle biopsy and fine needle biopsy had no difference (P>0.05). The rate ...
All of these patients were diagnosed by random prostate biopsy targeting 8 cores; that is, standard sextant cores and 2 additional cores from the bilateral anterior lateral horns. We evaluated the appropriate cut-off points of PPBC for predicting disease extension according to the number of biopsy...