In the field of immunotherapy also the liquid microenvironment deserves further study as a potential predictive marker. As a matter of fact, pre-treatment T-cell receptor repertoire metrics could predict response to pembrolizumab and immune-related toxicity [154]. By the way, the role of liquid ...
Intrinsic heterogeneity is one of the main factors hindering exosome analysis in body fluids. Single exosome detection may provide more accurate information of tumor progression (Fig.5E). Guo et al. presented an ssDNA-assisted single exosome detection platform. Rolling circle amplification (RCA) contri...
- in cases where the whole or a high proportion of the mammographic lesion has been removed, a small metal marker clip is deployed at the biopsy site. MR-guided vacuum biopsy is performed on Siemens MR scanners (Impact Expert and Vision) using a dedicated breast biopsy coil and a VB-devic...
exosomes remained in the central chamber. Moreover, two pairs of oscillators enabled the resuspension of particles into the liquid via transverse waves and acoustofluidic streaming, which effectively limited fouling and particle aggregation [86]. In addition, tangential flow filtration (TFF) is a tec...
A total of 8 US-guided 14-G core biopsies were obtained in the operating room before surgery close to the marker placed centrally in the tumor area at diagnosis (no attempt was made to remove the marker); and compared with the surgical specimen of the breast; primary outcome was the FNR...