Lung cancerBiomarkersCirculating tumor DNALung cancer is the leading cause of cancer-related mortality worldwide. Early cancer detection plays an important role in improving treatment success and patient prognosis. In the past decade, liquid biopsy became an important tool for cancer diagnosis, as ...
MicroRNAs, among the most extensively studied ncRNAs in oncology research, can be identified through various liquid biopsy techniques that detect miRNAs released by CTCs and tumor cells [51]. Detecting miRNAs is of paramount importance as biomarkers for the diagnostic assessment of lung cancer. For i...
To date, undoubtedly, tissue biopsy represents the gold standard for lung cancer diagnosis and cannot be replaced by liquid biopsy. However, scarcity of tumour tissue is common, with over 40% of patients needing more than one procedure in order to achieve a definitive diagnosis of lung cancer [...
lung cancer is often clinically classified into non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). NSCLC is the major pathological subtype of lung cancer, accounting for ~85% of all lung cancers. Standard therapy for lung cancer relies on the stage...
In August 2020, the FDA approved Guardant360® CDx for comprehensive genomic profiling in patients with any solid malignant cancer. The assay is also approved as a companion diagnostic to detect EGFR mutations in patients with non–small cell lung cancer (NSCLC) who could potentially benefit ...
Percutaneous Needle Aspiration Biopsy of Mediastinum for Staging of Lung Cancer Percutaneous needle aspiration (PCNA) of mediastinal masses is a complementary method in the staging of lung cancer. It is safe, efficient, and inexpensive... M Tercelj???Zorman,I Kern - 《Journal of Bronchology & ...
Several months (an average of 12.86 months) after perineal needling of the cancerous prostate for the purpose of obtaining tissue for biopsy, a tumor nodul... FS Haddad,AA Somsin - 《Journal of Surgical Oncology》 被引量: 66发表: 1987年 [Tumor seeding of the abdominal wall after fine ne...
Currently, immunotherapy for lung cancer mostly refers to the application of immune checkpoint inhibitors. Immune checkpoints are a large group of molecules expressed in immune cells, antigen-presenting cells, tumor cells, etc. and play a role in inhibiting or activating the acquired immune system,...
The aim of the present study was to evaluate the significance of lung biopsy for the modification of the treatment strategy in breast cancer patients who develop lung nodules during follow-up after breast surgery. Of 53 consecutive patients who underwent lung biopsies in two institutions (Hiroshima...
Molecular testing for genomic variants is recommended in advanced non-small cell lung cancer (NSCLC). Standard tissue biopsy is sometimes infeasible, procedurally risky, or insufficient in tumor tissue quantity. We present the analytical validation and c