One of the major challenges in cardiovascular disease is the identification of reliable clinical biomarkers that can be routinely measured in plasma. MicroRNAs (miRNAs) were recently discovered to circulate in the bloodstream in a remarkably stable form. Because of their stability and often tissue- ...
The purpose of this study was to compare biomarkers of cardiovascular disease risk in men who perform physical activity in accordance with these recommendations with those who do not.128 healthy men, aged 40-65 years, were recruited. 61 were classified as active (performing at least the minimum...
Biomarkers of cardiovascular disease risk in 40-65-year-old men performing recommended levels of physical activity, compared with sedentary men. Both the UK Department of Health and the US Centers for Disease Control and Prevention have recommended at least 30 minutes of moderate-intensity physical ...
Subsequently, each PRS was tested for association with prevalent cases of cardiovascular disease in 395,758 unrelated European ancestry UKB participants who were not in the GWAS meta-analysis (adjusting for sex, age, and 10 genetic principal components). We used a Bonferroni corrected threshold to ...
Some nuclear circRNAs regulate the transcription of host genes. Lastly, some circRNAs can even code for proteins. IRES: internal ribosome entry site. Acta Pharmacologica Sinica www.chinaphar.com Bayoumi AS et al Table 1. Circular RNA-microRNA-target gene axis in cardiovascular diseases. Disease ...
Vice Chairman of Academic Affairs Inova Heart and Vascular Institute Falls Church, VA Join us for the Biomarkers and Personalized Medicine in Cardiovascular Disease Symposium This outstanding annual event is designed to provide the latest clinical data, guidelines and evidence related to the clinical app...
Get a quick, expert overview of the ways in which biomarkers can be used to assess and guide the management of cardiovascular disease in the clinical setting. This concise, clinically-focused resource by Dr. Vijay Nambi consolidates today’s available information on this rapidly changing topic int...
Both hypertension and inflammation are major risk factors for cardiovascular disease (CVD) in HDD-CKD patients. In this study, we assessed the efficacy of a direct renin inhibitor, aliskiren, on blood pressure (BP) and CVD predictive biomarkers, such as brain natriuretic peptide (BNP), high-...
A cell reprograming approach for treatment of cardiovascular diseases will revolutionize the field of medicine and significantly expand the human lifetime. Availability of a comprehensive catalogue for cardiac biomarkers is necessary for developing cell reprograming modalities to treat cardiac diseases, as ...
Cardiovascular disease such as ischemic heart disease is a major contributor to the global burden of disease and the socioeconomic health costs. Clinical and epidemiological data show an association of typical oxidative stress markers such as lipid peroxidation products, 3-nitrotyrosine or oxidized DNA/...