So, cardiac biomarkers could be tested in patients presenting chest pain to confirm whether heart attack or Acute Myocardial Infarction (AMI) is onset or not. Myoglobin, Troponin-I and CK-MB are sensitive biomarkers for diagnosing heart attack/ AMI within specific time frames. In this work, a...
NT-proBNP is a marker of heart failure and increases when myocardial cells are damaged or when the heart is under increased load, making it a predictive marker for cardiovascular death. Within the range of NT-proBNP values, the mortality rate for CVD is higher than that for diabetes, further...
This is the largest study of biomarkers in acute stroke diagnosis and provides promising candidates for future panels. Article CAS PubMed Google Scholar Penn, A. M. et al. Validation of a proteomic biomarker panel to diagnose minor-stroke and transient ischaemic attack: phase 2 of SpecTRA, a...
Exploring the use of biomarkers to better understand what is going on in the body began with the link between troponin and suspected heart attack. Although it took years for troponin to be officially adopted as the standard of care, it did occur in 2007 – and the same could happen fo...
These two illuminating studies indicated a poten- tial use of miRNAs as biomarkers to predict heart attack for apparently healthy people. With the popularization of physi- cal examinations and the development of personalized medi- cine, the establishment of miRNAs as biomarkers to predict the ...
For instance, as per the May 2024 update by Heart Disease Facts published by the Centers for Disease Control and Prevention, in the United States, approximately 805,000 individuals experience a heart attack annually. Of these, 605,000 are encountering their first heart attack, while 200,000 are...
By only focusing on its inflammatory function, the scientists have been able to show that for two major risk groups, IL-6 is often key for heart attacks occurring. For smokers and people with high blood pressure, their lifestyle is not always the direct cause of the heart attack. Instead,...
Trimethylamine-N-oxide (TMAO) is a product of dietary, gut microbiome, and tissues metabolism. Elevated blood TMAO levels are associated with heart attack, stroke and chronic kidney disease (CKD). The purpose of our study was to investigate the gut microbiota associated with trimethylamine (TMA)...
Early detection of cardiac biomarkers for diagnosis of heart attack is the key to saving lives. Conventional method of detection like the enzyme-linked immunosorbent assay (ELISA) is time consuming and low in sensitivity. Here, we present a label-free detection system consisting of an array of ...
These two illuminating studies indicated a potential use of miRNAs as biomarkers to predict heart attack for apparently healthy people. With the popularization of physical examinations and the development of personalized medicine, the establishment of miRNAs as biomarkers to predict the incidence of heart...