One of the major challenges in cardiovascular disease is the identification of reliable clinical biomarkers that can be routinely measured in plasma. MicroRNAs (miRNAs) were recently discovered to circulate in the bloodstream in a remarkably stable form. Because of their stability and often tissue- ...
Subsequently, each PRS was tested for association with prevalent cases of cardiovascular disease in 395,758 unrelated European ancestry UKB participants who were not in the GWAS meta-analysis (adjusting for sex, age, and 10 genetic principal components). We used a Bonferroni corrected threshold to ...
Accordingly, this review will: 1) define the use of the present state-of-the-art biomarkers for the diagnosis of patients with acute cardiovascular disease; 2) touch on markers of historical interest whose use should be diminishing or eliminated; and 3) identify emerging markers, and 4) ...
ALD is a common chronic liver disease that frequently leads to cirrhosis1. With rising incidence rates, ALD has become the leading indication of liver transplantation2and is responsible for more than half of all liver-related deaths3,4. ALD progresses through a range of histological lesions, star...
elsevier editor: vijay nambi language: english paperback isbn: 9780323548359 9 7 8 - 0 - 3 2 3 - 5 4 8 3 5 - 9 get a quick, expert overview of the ways in which biomarkers can be used to assess and guide the management of cardiovascular disease in the clinical setting. this ...
The field of metabolomics and its applications to cardiovascular disease has evolved rapidly.6 Prior studies provided the first steps toward identification of metabolic disturbances in cardiovascular disease, suggesting a potential added value of metabolites as biomarkers for CHD.7-14 The aim of this ...
Recently, it is a typical disease marker of cardiovascular diseases for its remarkable significance in clinic and pathology. The role of CRP, as a research and therapeutic reagent, has been fully clarified by the current booming of researches in various diseases and related conditions. Studies have...
Conditions including cancers, cardiovascular and metabolic diseases will be the focus of study. This section will promote the innovation and development of disease-specific biomarkers by integrating multidisciplinary aspects of science. Studies considered for publication include those regarding the development ...
Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring. JAMA. 2004;291(18):2204-2211. doi:10.1001/jama.291.18.2204 ArticlePubMedGoogle ScholarCrossref 5. Wilmot KA, O’Flaherty M, Cape...
We still need to identify more novel biomarkers to supplement ECG or X-rays and provide more accurate and sensitive methods for cardiovascular disease diagnosis, risk stratification, and management.Conflicts of Interest The authors declare that they have no conflicts of interest....