One of the major challenges in cardiovascular disease is the identification of reliable clinical biomarkers that can be routinely measured in plasma. MicroRNAs (miRNAs) were recently discovered to circulate in the bloodstream in a remarkably stable form. Because of their stability and often tissue- ...
The accurate diagnosis and prevention of cardiovascular disease (CVD) is an important public health goal. Although clinical characteristics such as age and gender are well-established risk factors for CVD, such features are not sufficient to identify all patients at risk. Cardiovascular biomarkers have...
Subsequently, each PRS was tested for association with prevalent cases of cardiovascular disease in 395,758 unrelated European ancestry UKB participants who were not in the GWAS meta-analysis (adjusting for sex, age, and 10 genetic principal components). We used a Bonferroni corrected threshold to ...
Nontraditional risk factors and biomarkers for cardiovascular disease: mechanistic, research, and clinical considerations for youth: a scientific statement... The rapid increase in the prevalence and severity of obesity in children is likely to lower the age of onset and increase the incidence of ...
Both hypertension and inflammation are major risk factors for cardiovascular disease (CVD) in HDD-CKD patients. In this study, we assessed the efficacy of a direct renin inhibitor, aliskiren, on blood pressure (BP) and CVD predictive biomarkers, such as brain natriuretic peptide (BNP), high-...
Novel Biomarkers of Cardiovascular Disease 来自 Springer 喜欢 0 阅读量: 32 作者: TS Welch 摘要: The accurate identification of patients at increased risk for future cardiovascular events is challenging. Commonly utilized risk prediction tools, such as the Framingham risk score, rely on a small ...
Gonadotrophin releasing hormone (GnRH) agonists and antagonists reduce testosterone levels for the treatment of advanced and metastatic prostate cancer. Androgen deprivation therapy (ADT) is associated with increased risk of cardiovascular (CV) events and CV disease (CVD), especially in patients with pre...
Cardiovascular disease such as ischemic heart disease is a major contributor to the global burden of disease and the socioeconomic health costs. Clinical and epidemiological data show an association of typical oxidative stress markers such as lipid peroxidation products, 3-nitrotyrosine or oxidized DNA/...
Autoimmune diseases are associated with a dramatically increased risk of atherosclerotic cardiovascular disease and its clinical manifestations. The increa... F Porsch,CJ Binder - 《Nature Reviews Cardiology》 被引量: 0发表: 2024年 The importance of the omega-6/omega-3 fatty acid ratio in cardiova...
A cell reprograming approach for treatment of cardiovascular diseases will revolutionize the field of medicine and significantly expand the human lifetime. Availability of a comprehensive catalogue for cardiac biomarkers is necessary for developing cell reprograming modalities to treat cardiac diseases, as ...