candida is well established as a soil ecotoxicological model species since the 1960s (van Gestel, 2012); (3) its genome has been sequenced and annotated facilitating the development of molecular tools for studying its genomic responses to pollution (Faddeeva-Vakhrusheva et al., 2017), and (4...
Clinical and genomic characterization of treatment-emergent small-cell neuroendocrine prostate cancer: a multi-institutional prospective study. J Clin Oncol. 2018;36(24):2492–503. Article CAS PubMed PubMed Central Google Scholar Scher HI, Morris MJ, Stadler WM, Higano C, Basch E, Fizazi K,...
DNA was extracted from FFPE tissue samples and tissue-derived cells using the PureLink Genomic DNA Mini Kit (cat# 1820-00, Invitrogen, ThermoFisher Scientific). The TaqMan™ RNase P Detection Reagents Kit (cat# 4316831, ThermoFisher Scientific) was used, as per the manufacturer’s instructions...
A subset of triple-negative breast cancers (TNBCs) have homologous recombination deficiency with upregulation of compensatory DNA repair pathways. PIKTOR, a combination of TAK-228 (TORC1/2 inhibitor) and TAK-117 (PI3Kα inhibitor), is hypothesized to increase genomic instability and increase DNA ...
Assessing the clinical utility of cancer genomic and proteomic data across tumor types. Nat. Biotechnol. 32, 644–652 (2014). Article CAS PubMed PubMed Central Google Scholar Saito, M. et al. The association of microRNA expression with prognosis and progression in early-stage, non-small ...
Assessing the clinical utility of cancer genomic and proteomic data across tumor types. Nat. Biotechnol. 32, 644–652 (2014). Article CAS PubMed PubMed Central Google Scholar Saito, M. et al. The association of microRNA expression with prognosis and progression in early-stage, non-small ...
Amplicons of 1.8 kb (Figure 1a) and 3.6 kb (Figure 1b) were amplified from cDNA and genomic DNA, respectively. After DNA sequencing, intron–exon analysis revealed that theTrCNX1genomic sequence comprised of six exons (E) and five introns (I) in its gene coding region (Figure 1b). NCBI...