degree in life sciences from MIT and who now serves on the faculty of UCSF - received a Nobel prize in physiology or medicine. Next:1. Harvard University 11/15 Credit 1. Harvard University Location: Cambridge, Massachusetts Best Global Universities overall rank: 1 Fact...
Importantly, we found that ATAC-seq peaks in patient breast tumours that are occupied by both ER and MAF in MCF7 cells are functionally connected to control of the E2 target gene expression through promoter–enhancer connections, to a higher degree than expected by chance (for example, SOX9 ...
S. Psychiatric ‘diseases’ versus behavioral disorders and degree of genetic influence. Psychol. Med. 41, 33–40 (2011). Article CAS PubMed Google Scholar Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new ...
Category OWNER: EAW Name: Jon S. Gethner Degree: Ph.D. Specialty: Chemical Physics, Spectroscopy, Instrumentation & Automation e-Mail: JGethner1@analyze.com Phone: +1 212 393 9540 Affiliation: Adaptive Analyzer Technologies, Inc, OWNER Dr. Anamika Sarkar
ArticleCASPubMedGoogle Scholar Ahmed, F. E.&Setlow, R. B.(1978) Excision repair in ataxia telangiectasia, Fanconi's anemia, Cockayne syndrome, and Bloom's syndrome after treatment with ultraviolet radiation andN-acetoxy-2-acetylaminofluorene.Biochim. Biophys. Acta521, 805–17. ...
In contrast, the disease-associated amyloids discussed in the following examples have functions that are detrimental to the organism and structures that are not as easily characterized due to their high degree of polymorphism arising from their metastable nature. Distinct Aggregates, Distinct Activities ...
It is thought that gene duplication led to a high degree of diversity among the specialized metabolites [84]. 3.2. Dynamics of Plant Metabolites in Response to Stresses Abiotic and biotic stresses have been a constant threat to crop production affecting plant growth and development, including ...
‘clock’ metrics, such as DNA methylation age and epigenetic age acceleration, which describe the degree to which predicted biological age deviates from chronological age. In turn, these epigenetic clock metrics have emerged as novel biomarkers of a host of phenotypes such as allergy and asthma ...
DNA methylation has been implicated in the regulation of the immune response to mastitis [29,30], lipopolysaccharide [31] andMycobacterium bovis[32]. These studies have started to characterise epigenetic signatures related to infection, yet the degree of natural epigenetic variation in the immune syst...
3c,g); the decrease affected follicular but not marginal B cells and to a minor degree plasma cells (Fig. 3c,h). Spleen macrophages (Ly6Clo/−Gr-1lo/−) were reduced, whereas monocytes were shifted towards a Ly6CintmGr-1hi population (Fig. 3d and Extended Data Fig. 4g). We ...