combinations on the growth ofS. miltiorrhiza, we designed thirty-one different inoculation treatments using the method of complete factorial design. The inoculums of different treatments were evenly mixed in equal amounts to prepare 200 spores per 10 g of soil according to the design scheme in ...
With the rapid advancements in spatial transcriptome sequencing, multiple tissue slices are now available, enabling the integration and interpretation of spatial cellular landscapes. Herein, we introduce SpaDo, a tool for multi-slice spatial domain analy
Landmark configurations were aligned by generalized Procrustes superimposition using the gpagen function in the R package geomorph [110]. This minimizes the bending energy differences among landmark constellations by translating them to a shared centroid position, scaling them to a unit centroid size, ...
In terms of glutamatergic afferent projections reaching the STN, analysis of human brain tissue has identified VGLUT1 protein, indicative of afferent terminals from the cortex (and possibly other excitatory brain areas positive for this subtype of VGLUT), localized to the dorso-caudal extent of the...
However, these aspects have a lower potential for biomimetic material systems and few parallels can be drawn with other artificial material systems; they are therefore not discussed further in this paper. 3.2. Resilience through Self-Repair of Damage The self-repair of wounds is a typical life-...
1. Introduction The main question of this paper is whether and why molecular biology can be considered a discipline of its own. (This paper is in parts a translation and adaptation of my 2012 bachelor’s thesis at the University of Salzburg under Michael Breitenbach’s supervision. When discuss...
Gene expression inference with deep learning [github][paper] This deals with a specific prediction task, namely to predict the expression of specified target genes from a panel of about 1,000 pre-selected “landmark genes”. As the authors explain, gene expression levels are often highly correla...
Explaining contrasting patterns of distribution between related species is crucial for understanding the dynamics of biodiversity. Despite instances where hybridization and whole genome duplication (WGD) can yield detrimental outcomes, a role in facilita
The first lineage choice in human embryo development separates trophectoderm from the inner cell mass. Naïve human embryonic stem cells are derived from the inner cell mass and offer possibilities to explore how lineage integrity is maintained. Here,
S3). We found that our filtering scheme did not affect the enrichment scores (Additional File 1: Fig. S3A). We also explored whether some of our filters (age, tumor purity, necrosis etc.) had any impact on the enrichment scores, finding, unsurprisingly, that a higher tumor purity is ...