The extracellular matrix (ECM) is an intricate network composed of an array of multidomain macromolecules organized in a cell/tissue-specific manner. Components of the ECM link together to form a structurally stable composite, contributing to the mechanical properties of tissues. The ECM is also a...
The biology of the extracellular matrix: novel insights Purpose of review;Extracellular matrix (ECM) has both structural and regulatory roles. This update reviews the representative recent developments in divers... D Hubmacher,SS Apte - 《Current Opinion in Rheumatology》 被引量: 161发表: 2013年...
The cell biology of the extracellular matrix by Elizabeth D Hay. pp 468. Plenum Press, New York. 1991. $89: ISBN 0-306-43951-4No abstract is available for this article.doi:10.1016/0307-4412(92)90083-XH KnaggsJohn Wiley And Sons, Inc....
英国谢菲尔德大学的研究人员发现,乳腺癌细胞通过摄取和消耗周围的基质来克服饥饿。这一发现揭示了一种以前未知的癌细胞存活机制,并可能为治疗发展提供新的靶点。 该研究结果发表在《PLoS Biology》杂志上的一篇题为“The extracellular matrix supports breast cancer cell growth under amino acid starvation by promoting ...
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Chapters 6 through 19, from "Basic Genetic Mechanisms" to "Cell Junctions, Cell Adhesion, and the Extracellular Matrix" are covered in this way.-- Completely reorganized to match the Third Edition of Molecular Biology of the Cell.-- Contains 50 new problems, including an entirely new chapter ...
Cell - Matrix, Proteins, Biology: Matrix proteins are large molecules tightly bound to form extensive networks of insoluble fibres. These fibres may even exceed the size of the cells themselves. The proteins are of two general types, structural and adhes
The extracellular matrix (ECM) is a key component of the stem cell niche and is now emerging as more than just an inert scaffold. Indeed, new technologies have provided mechanistic insights into the effects of the ECM on stem cell fate choice. The field
Matrix Biologywas established in 1980 asCollagen and Related Research, an international scientific journal for publication of research on the extracellular matrix. The journal becameMatrix… $4620 Article publishing charge for open access 5 days
研究意义：组织纤维化和并发的胞外基质（Extracellular matrix，ECM）变硬与肝细胞癌、胰腺导管腺癌和乳腺癌等癌症进展有关。已知高硬度ECM可促进细胞增殖、上皮间质转化、迁移和化学耐药，这与胞外基质硬度增加导致细胞所受张力增加有关。具体机制则是细胞膜中的整合素蛋白（Integrins）感应ECM硬度，通过调节细胞黏附分子...