4d,e). Consistent with its expression in patient samples, CTNNB1 3′ SP was upregulated in HCC cell lines, Hep3B and SNU398, compared with THLE-2 (Fig. 4f). We also verified that CTNNB1 3′ SP is conserved in mouse and is more highly expressed in the mouse tumour relative to ...
Nature Cell Biology volume 26, pages 946–961 (2024)Cite this article 8562 Accesses 7 Citations 2 Altmetric Metrics details Abstract RNA-binding proteins (RBPs) are pivotal in acute myeloid leukaemia (AML), a lethal disease. Although specific phase separation-competent RBPs are recognized in ...
et al. Intrinsically disordered segments affect protein half-life in the cell and during evolution. Cell Rep. 8, 1832–1844 (2014). Article PubMed PubMed Central Google Scholar Uversky, V. N. Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated ...
Regulation of tumor cell metastasis Human Specimens, Cell lines (HeyA8, Ovcar5, Tyk-nu, Snu119, and Kuramochi) 2019 Sean McGuire [70] Regulation of tumor cell motility Cell lines (ES-2, SK-OV-3 and NOE) 2020 Masato Yoshihara [71] Pancreatic cancer FSCN1 Diagnosis biomarker Human Specimens...
The efficiencies of overexpression were detected by western blot. To obtain cell lines stably overexpressing RAB11B-AS1, SNU-398, and HepG2 cells with transfected with RAB11B-AS1 overexpression vector. The transfected cells were treated with 800 µg/ml neomycin to select RAB11B-AS1-overexpressed...
8E, F). Importantly, it was present at the wing hinge and at the proximal rim of the marginal cell of the wing blade but not in the wing articulation (Fig. 8C). Hence, some Cpr56F-GFP signal coincided with regions of Pro- Resilin-GFP expression, but some did not. Interestingly, ...
Kim JD, Kim JM, Pyo JO, Kim SY, Kim BS, Yu R, Han IS (1997) Capsaicin can alter the expression of tumor forming-related genes which might be followed by induction of apoptosis of a Korean stomach cancer cell line, SNU-1. Cancer Lett 120:235–241 Article PubMed CAS Google Scholar ...
ASB9 interacts with the creatine kinase system and negatively regulates cell growth. The differential expression and function of ASB9 and ASB9ΔSOCS may be a key factor in the growth of human cell lines and primary cells.Background The largest family of suppressor of cytokine signalling (SOCS)...
International Journal of Molecular Sciences Review Vascular Endothelial Cell Biology: An Update Anne Krüger-Genge 1,2,*, Anna Blocki 3 , Ralf-Peter Franke 4 and Friedrich Jung 5 1 Department of Biomaterials and Healthcare, Division of Life Science and Bioprocesses, Fraunhofer Institute for ...
We offer a diverse in vitro screening panel of over 600 authenticated, well-validated human cancer cell lines across 30 cancer types. Our cancer cell line panel provides powerful tools for cancer research and drug discovery. Key features of the WuXi cancer cell panel include:...