Review ReportsVersions Notes Abstract Past-oriented rumination and future-oriented worry are two aspects of perseverative negative thinking related to the neuroticism endophenotype and associated with depression and anxiety. Our present aim was to investigate the genomic background of these two aspects of...
Proteins are the key molecules of the cell that are involved in all cellular processes. The three-dimensional (3D) shape of a protein provides critical information that can, among many things, be used to study protein interactions, functions and the impact of missense variation. Although tremendou...
With the rapid advancements in spatial transcriptome sequencing, multiple tissue slices are now available, enabling the integration and interpretation of spatial cellular landscapes. Herein, we introduce SpaDo, a tool for multi-slice spatial domain analy
For three candidate sites in blood, we demonstrate the stable expression of transgene without disrupting nearby genes in host erythroid cells. We also develop a computer program, Genomics and Epigenetic Guided Safe Harbor mapper (GEG-SH mapper), for knowledge-based tissue-specific genomic safe ...
Also, make sure you include all the important reactions in your notes as they are an important part of the NEET notes for Chemistry. The students must check all concepts which are included in the short form in the notes. Make sure you solve the NCERT problems before appearing in the ...
Full size image Early gastruloids recapitulating the formation of three germ layers Fig. 3: Schematic representation of the in vivo embryo and corresponding in vitro models of the post-implantation stages. In vivo developmental stages of the mouse and human embryos are depicted in the middle, fr...
3B). Comparing topologies based on the three datasets, we observe that the N-SPS and N-Atlantic lineages form a monophyletic clade in the more permissive dataset (Fig. 3B, Fig. S11), while this monophyly is not recovered in the “full” and more stringent datasets (Figs. S12, S13). ...
For ENO three different isoenzymes also occur in vertebrate tissues, termed α, β and γ. The active enzyme is a homo- or heterodimer. The α form is present in many tissues, especially in the liver, β predominates in muscle and γ is only found in brain cells. The topologies for the...
For example, the 'notes' fields are examined, as they usually contain some information describing the model elements to which they are attached. 3. Finally, because it is impractical for BioModels Database to duplicate and keep up-to-date all relevant information available from model cross-...
sides of the three perspectives together form the six meaning facets illustrated in the “meaning diamond” (Figure1). In order to represent the complete meaning of a bio-model one has to specify the intrinsic and extrinsic side of each of the three perspectives and the connections between ...