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Q. A. Wang, L. Rui, J. Liu andY. Liu*(2024). "Mammalian IRE1α dynamically and functionally coalesces with stress granules."Nature Cell Biology26(6): 917-931.(20240507,武汉大学,刘勇)揭示了IRE1α在细胞抗逆应激
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Data availability The data supporting the findings of this study are available within the article and the Supplementary Information. Source data are provided with this paper.References Zeman, M. K. & Cimprich, K. A. Causes and consequences of replication stress. Nat. Cell Biol. 16, 2–9 (...
We celebrate the 25th anniversary of Nature Cell Biology with a series of commissioned content and an online collection of research articles across the journal's broad scope. We look back at biological discoveries and discuss the roles of cell biologists in sustainability, our ongoing commitments to...
Automatic cell type annotation methods are increasingly used in single-cell RNA sequencing (scRNA-seq) analysis due to their fast and precise advantages. However, current methods often fail to account for the imbalance of scRNA-seq datasets and ignore in
Class I primed hPSCs obtain two active Xs with no XIST expression. Class II and III hPSCs both have undergone XCI. The inactive X of Class II primed hPSCs is coated with XIST, whereas almost no expression of XIST in Class III primed hPSCs, leading to exposing of the original inactive ...
[10], or predict gene expression levels in a sample using histology imaging [11,12]; one such example is the mapping of somatic mutations, such as those found in cancer, to a cellular phenotype such as the emergence of dense cancerous tissue that is easily identifiable in pathology imaging...