L. cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins. Proc. Natl Acad. Sci. USA 112, E7176–7185 (2015). Article CAS PubMed PubMed Central Google Scholar Djakovic, S. N., Schwarz, L. A., Barylko, B.,...
& Chen, M. The role of cAMP-PKA pathway in lactate-induced intramuscular triglyceride accumulation and mitochondria content increase in mice. Front. Physiol. 12, 709135 (2021). Article PubMed PubMed Central Google Scholar Constantin-Teodosiu, D., Howell, S. & Greenhaff, P. L. Carnitine ...
Camp, J. Rapola, P. Santavuori, S.L. Hofmann, L. Peltonen Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis Nature, 376 (1995), pp. 584-587 View in ScopusGoogle Scholar [11] L.A. Camp, S.L. Hofmann Purification and properties of a ...
calcium ions, cyclic adenosine monophosphate (cAMP) or other ligands [28,50,108,126]. Despite their reduced number in fungi as compared to animals, the downstream signal transduction wiring is equally complex and facilitates a multitude of cellular responses. It is still under debate whether plants...
Section 1.1 The Study Of Life Reveals Unifying Themes1.2 The Core Theme: Evolution Accounts For The Unity And Diversity Of Life1.3 In Studying Nature, Scientists Make Observations And Form And Test Hypotheses1.4 Science Benefits From A Cooperative Approach And Diverse ViewpointsChapter Questions ...
near cell type pairs and 9 far cell type pairs according to their relative spatial positions (Additional file1: Fig. S6f). The nicely organized layer structures lead to the majority of cell types being close to each other, such as L4 and L5 IT, L6b, and L6 IT (Additional file1: Fig...
(MRFs), and cAMP response element-binding protein (CREB), which are important for skeletal muscle mass and function regulation [3]. Members of theFOXOprotein family regulate processes such as cell cycle, apoptosis, and muscle development and repair [31], whereFOXO1andFOXO3are pivotal in ...
(2002) demonstrated reduced neuronal activity during periods of sleep. This was later supported by studies using GCaMP to measure Ca2+levels (Bushey et al.2015). In addition, van Alphen et al. (2013) demonstrated varying levels of electrical activity during sleep bouts and showed that these ...
Camp, J. G. et al. Multilineage communication regulates human liver bud development from pluripotency. Nature 546, 533–538 (2017). Article CAS PubMed Google Scholar Cohen, M. et al. Lung single-cell signaling interaction map reveals basophil role in macrophage imprinting. Cell 175, 1031–10...
The 9-1-1 DNA checkpoint clamp is loaded onto 5′-recessed DNA to activate the DNA damage checkpoint that arrests the cell cycle. The 9-1-1 clamp is a heterotrimeric ring that is loaded in Saccharomyces cerevisiae by Rad24-RFC (hRAD17-RFC), an alternate