During the training process, the Adam optimizer was used with the learning rate of 1e−4 and the decay rate of 1e−5. Other network structures were also tested, including long short-term memory (LSTM) and gated recurrent unit (GRU). They have similar performances. Therefore, we kept ...
B. Entry tropism of BK and Merkel cell polyomaviruses in cell culture. PLOS ONE 7, e42181 (2012). CAS PubMed PubMed Central Google Scholar Kwun, H. J., Chang, Y. & Moore, P. S. Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence. Proc. ...
Log-normalisation was used for both gene and peak counts, and respective values for highly variable features scaled and centred to zero mean and unit variance were then used as input to discussed algorithms such as PCA, as implemented in scikit-learn [55] and scanpy [9], or MOFA+ [30]....
Understanding the chronological and biological drivers of these DNA methylation clocks will require them to be teased apart as much as possible (see Fig.1b). The clear separation between these two factors, down to specific sets of CpGs, would lead to more powerful specialized clocks and distinct...
Unit for Addiction Medicine, Institute of Psychiatry, University of Oslo,Linda OlsenNorwegian Institute of Public Health, Division of Forensic Toxicology and ... H Waal,G Frogopsahl,L Olsen,... - 《European Addiction Research》 被引量: 86发表: 2006年 Functional changes in dopamine D3 receptors...
Fig. 4 Distribution of synonymous distances among paralogs for grape vine phylloxera (panela,D. vitifoliae),pea aphid (panelb,A. pisum), and fruit fly (panelc,D. melanogaster). Paralogs were identified as RBH pairs, with an iterative approach allowing to cover both recent duplications (termin...
Each dot represents a repeat unit within a raw PacBio read and is graphed according to monomer length and overall (tandem) repeat length. A distinct distribution surrounding a 53 bp monomer was observed (including tandem repeats divisible by 53 bp). b The 53 bp monomer (Mm53) was ...
4). Secondly, features accompanying the core TULIP domain indicate that the overall unit evolved once from a common origin. The key observation here is that bacterial TULIP domains have three additional β-strands, one coded before the domain and two after, that form 6 stranded β-meanders for...