DeepChem is a "... [P]ython library that aims to make the use of machine-learning in drug discovery straightforward and convenient" which checks a lot of boxes when it comes to advanced deep learning: one-shot learning, graph convolutional networks, learning from less data, and LSTM embeddin...
We observed that SpaDo exhibited tolerance to higher dropout rates, while other methods were notably affected (Fig. 3g, h and see “Methods”). SpaDo effectively mitigates batch effects in multi-slice integration Most existing spatial transcriptome analysis methods are limited to single-slice ...
This process has been greatly advanced by the use of computational tools, such as deep learning87. However, there are some risks associated with codon optimization that should be considered when applying this process to vaccine design. For example, too rapid translation can result in misfolded ...
BiologyCollege ScienceCurriculumEnvironmentHigher EducationIndependent StudySociologyStudent ProjectsThe Cambridge Advanced level GCE Examination1 in Social Biology includes an individual study (project). The system by which project topics are submitted, modified, and approved is outlined in this paper and an...
This indicates that students who rated the learning with the BioScientist positively had more advanced inquiry skills and were more motivated to learn. Regarding the positive correlation between the program evaluation and intrinsic motivation variables, it can be assumed that students with greater intrins...
Advanced Research Institute of Multidisciplinary Science, Beijing Institute of Technology, No. 5, South Zhongguancun Street, Haidian District, Beijing, 100081, China Bin Liu Contributions H.W.L was involved in the implementation, programming, manuscript writing, and correcting. K.Y was involved in th...
Starting in 2022, CAS and Australia's Commonwealth Scientific and Industrial Research Organization (CSIRO) launched a joint project for advanced near shore plankton monitoring to boost the Blue Economy. The initiative involves multip...
Due to a lack of sufficiently advanced detection technologies, the role and effect of repeats in genomes, especially the human genome, have been underestimated. We believe that this review will be helpful in the understanding of repeats in genomes and provide guidance for repeat annotation (...
All X-ray diffraction data were collected using beamline 24-ID-E of the Advanced Photon Source (APS) at Argonne National Laboratory, using a beam wavelength of 0.971 Å and temperature of 100 K. Data were collected using 5° oscillations with a detector distance of 140 mm, using...
We designed two CRISPR guide RNAs for each locus and chose the one with higher editing efficiency for the cassette integration (editing efficiency for all gRNAs are greater than 50%, Additional file 2: Table S1). GFP cassettes were integrated into the GSH loci through HDR-mediated insertion. ...