While each omics platform has the potential to capture a snapshot in a bone cell's lifetime or disease state, individually they lack the power and capacity to capture holistic and spatiotemporal changes that occur both at the cell and tissue level [2]. Recently, momentum has grown towards ...
The benefits of one-step NGS library preparation are: (i) high-throughput NGS sample preparation due to 5 hour shorter protocol; (ii) improved spec- ificity of NGS data due to skipping one PCR step in the protocol and, accordingly, reduced number of mutants in the ssODN library; (iii...
where gene promoter and gene body are included) and distal (other genomic regions out of proximal genic region) genomic regions on gene transcription activity during wheat vernalization, we further investigated the expression level of their corresponding...
When all row vectors stored in 10X-HDF5 are loaded at once, the calculation is fastest, but the memory usage is also highest. Because the calculation time and the memory usage have a trade-off and the user’s computational environment is not always high-spec, the block size should be opti...
Since yeast cell spheroplasts, lacking an intact cell wall and primary toxin receptors, are still phenotypically K28 sensitive, the existence of a secondary toxin receptor at the level of the yeast plasma membrane (PM) was proposed for a long time, but only recently identified. In this ...
All these models comprise a multi-level process. Models include societal issues (at local, regional, global levels) and inter- and multidisciplinary approaches as well as changes in pedagogy. ESD teaching and learning is a combination of different views and taking on different perspectives, ...
Generalist herbivores such as the two-spotted spider mite Tetranychus urticae thrive on a wide variety of plants and can rapidly adapt to novel hosts. What traits enable polyphagous herbivores to cope with the diversity of secondary metabolites in their
and the BP genes in order. And both the anchor genes and BP genes are much more actively transcribed than rest genes without H3K4me3 peak (Fig.3h). Moreover, a positive correlation between gene transcription level with chromatin interaction degree (interaction frequency) was observed in both V0...
A tree was composed of classification systems within dominant phyla at the genus level in MolecuFleTsL210.1T8,h2e3,a1b5u5n5 dances of taxa genera are over the top 30. The genera with bacterial β-1,3-glucanase5 of 19 are marked in red. Only the glycoside hydrolases selected from the ...
Design is usually hierarchical; while an integrated circuit designer may worry about the details of his silicon chip, a computer motherboard designer can take the behaviour of each chip for granted and concentrate only on the interconnections of chips of different kinds to perform a high-level ...