1875. Notes on some collections made from Furnas Lake, Azores, containing algae and a few other organisms. J. Linn. Soc. London Bot. (London) 14: 328–340. (florist., tax.-syst.) Article Google Scholar Ascione, R. 1966. The Use of Enzymes from Thermophilic Organisms to Investigate ...
Switch-like dynamics are widely exploited to control biological systems requiring memory and decision making (Tyson and Novák2010). The AM system can efficiently function as a bistable switch and its dynamics can be emulated by a large class of complex biological networks (Cardelli2014). AM works...
Biological networks constructed from varied data can be used to map cellular function, but each data type has limitations. Network integration promises to address these limitations by combining and automatically weighting input information to obtain a mo
According to the bispecific antibody classification13, our first design of bispecific antibodies belongs to the dAb-IgG group with an appended LC variable domain consisting of the heavy chain of pertuzumab and the LC of trastuzumab. Figure 1 Bispecific trastuzumab/pertuzumab plant biosimilars and SPR ...
Notes: peroxisome proliferator-activated receptor gamma (PPARγ), CCAAT enhancer-binding alpha protein (C/EBPα), interleukin-1β (IL-1β), interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-alpha), B-cell lymphoma (Bax), B-lymphoblastoma-2 gene (Bcl-2), matrix metalloproteinase (...
Different approaches were applied for the phylogenetic analysis of ZCKP2, and all these approaches had quite similar results. VIRIDIC classified ZCKP2 is the same genus as ZCKP8, but the intergenomic similarity was below the species clustering threshold. VIRIDIC classification is highly reliable sinc...
Given a classification task withKclasses, a classifier is a function that associates a class to an input vector:. In our workis a gene expression profile,is the predicted class corresponding to the phenotype andFis a deep neural network. In the context of gene expression data, we use a mul...
The WHO notes that this was the fastest identification made in the case of a new disease. The plan developed was a WHO-China joint plan, and the WHO urged the rest of the world to act immediately since China had given the world an opportunity to change the ...
et al. Classification of human colorectal adenocarcinoma cell lines. Cancer Res. 36, 4562–4569 (1976). CAS PubMed Google Scholar Zhang, S. et al. N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p2...
(hereafter, uninformative). Evidence chains of this class do not inform on therapeutic action, efficacy, or safety. Neither do they enable decision-making in a drug discovery programme and can be safely discarded. For example, the evidence generated for the drug Tobramycin as shown in Fig.1c...