Degree cutoff = 2, Node Score Cutoff = 0.2, and K- Core = 2 were set as the advanced settings. MCODE was applied to filtrate hub proteins within the PPI network. At last, the enrichment analyses of the DEGs in different modules were also conducted by the STRING database. Identification ...
The degree of each protein node was determined using the Cytoscape plugin CytoHubba Version 0.1 to filter out hub genes based on the connectivity. Hub gene analysis A GO enrichment chord diagram was drawn to reveal the differences of hub genes in biological functions using R package ggplot2. ...
[37]. The observed difference in the concentration-dependent MEL effect in hDPCs may be related to the high-dose MEL property to reduce the degree of oxidative stress-triggered protein glycosylation [38], which could explain the observed decrease in GDNF expression in vitro, in the presence of...
created by the “STRING database”. Each interacting node with the hub HSP70 represents the top 10 predicted functional protein partners with a high level of confidence. The average node degree was 13.8, the average local clustering coefficient was 0.82, and the PPI enrichmentp-value was <1.0 ...
saturation state (Fig.4). These data indicated that the evolution degree ofGELPsin cotton is conservative to a certain extent, and there is still a potential evolutionary expansion trend. Fig. 4 Saturation of base substitutions between nucleotide sequences of orthologous or paralogous gene pairs....
Standalone applications are more difficult to implement but they allow a higher degree of interactivity, and in general, for a much richer user experience than those that are web based. Java J2SDK [62] was chosen for client implementation to ensure portability through operative systems while ...