Results: Evidence indicated a permanent increase in the frequency of microbial biofilm in the central venous catheter, mechanical heart valve, and urinary catheter, as well as persistent infections. However, antimicrobial resistance induced by biofilms formation and the antimicrobial treatment of biofilms ...
10 μg total RNA of each sample was subjected to DNase I (Roche) treatment (as per manufacturer's instructions) followed by cDNA synthesis using Superscript III RT (Invitrogen). cDNA was diluted to the desired dilution and the real-time quantitative PCR was carried out using Applied ...
phenotype, indicating reduced extracellular matrix production. Biofilm time-kill assays demonstrated a four-log reduction in UPEC viability when treated with Tryptamine, highlighting its potent antibacterial properties, comparable to CFS treatment. Biofilm ROS assays indicated a significant elevation in ROS g...
These microcosmic communities profoundly affect a wide range of our daily lives. They directly lead to suppurative infection in humans, and they adhere to medical devices. Therefore, they are strongly associated with nosocomial infections, periodontitis, chronic wound changes, musculoskeletal infections (o...
Although biocides are widely used to control the detrimental formation of microbial biofilms, their efficacy is always disappointing when compared with disinfection assays performed with planktonic microorganisms (Costertonet al., 1987;Brown and Gilbert, 1993). In fact, different treatment plants have pe...
Di Luca, M., Maccari, G., & Nifosì, R. (2014). Treatment of microbial biofilms in the post-antibiotic era: Prophylactic and therapeutic use of antimicrobial peptides and their design by bioinformatics tools.Pathogens and Disease, 70(3), 257–270. doi:10.1111/2049-632X.12151. Epub 201...
When biofilms develop on synthetic membranes, the EPS layers add to the hydraulic resistance of the membrane and provides the embedded cells protection against chemical cleaning and nutrients after the chemical treatment (Flemming et al. 1997, Hijnen et al. 2012). Hence, membrane biofouling is a...
The spiral-shaped organism is known to induce a variety of clinical manifestations in humans, particularly acute and chronic skin lesions, arthritis, pericarditis, and inflammation of the central and peripheral nervous systems. Although antibiotic therapy is usually effective early in the disease, ...
K. Detection of Metallic Implant–associated Infections with FDG PET in Patients with Trauma: Correlation with Microbiologic Results1. Radiology 226, 391 (2003). Article PubMed Google Scholar Meffert, R. M. Maintenance and treatment of the ailing and failing implant. J. Indiana Dent. Assoc. ...
gingivalis biofilm in a subject comprising administering to the subject a pharmaceutical composition comprising an inhibiting agent of a polypeptide that reduces or inhibits biofilm formation and/or biofilm development. Also provided are compositions useful in the prevention, inhibition or treatment of ...