Cradle cap, also called seborrheic dermatitis, is a very common rash seen in newborns. The rash, usually seen in the first month of life, starts on the scalp and has a red, waxy, and scaly appearance. Sometimes the rash can extend to the face and neck. It is not generally itchy, and...
Metabolism of haem by-products such as bilirubin by humans and their gut microbiota is essential to human health, as excess serum bilirubin can cause jaundice and even neurological damage. The bacterial enzymes that reduce bilirubin to urobilinogen, a key step in this pathway, have remained unide...
conjugated bilirubin. This combination of reduced ability to convert bilirubin into bilirubin glucuronide in the liver and the easy permeability of the blood-brain barrier renders newborns/premature babies more susceptible to potential brain damage. One of the strategies to reduce this risk involves ex...
How it works: Specimens collected for totalbilirubinassessment in peripheral blood are most often serum in nature. While there are often slight differences between various manufacturers and kits (includinghigh performance liquid chromatographyandoxidasemethods), totalbilirubinassessment in adults using modern...
Possible mechanisms are proposed to explain the protective effect of bilirubin in clinical studies including anti- oxidant, anti-inflammatory and anti-apoptotic effects, suggesting that it could represent a potential therapeutic compound to reduce the prevalence of CKD or cardiovascular disease10. However...
However, jaundice affects your appearance and can be distressing and because of this you may want to do something about it. It is not recommended that you reduce your dose of atazanavir to reduce bilirubin levels. The safest way to treat jaundice caused by hyperbilirubinaemia if you are taking...
as it causes minimal discomfort and is less invasive. The inconvenience, pain, and difficulty associated with the fingerstick method, particularly in newborns, make non-invasive testing an attractive alternative. Moreover, non-invasive testing methods reduce the risk of infections, as they do not ...
In the lower small intestine and colon, bacteria remove glucuronic acid residues and reduce bilirubin to the colorless urobilinogen and stercobilinogen. Exposure to air oxidizes these to urobilin and stercobilin, respectively, (i.e., red-orange pigments that contribute to the normal color of ...
Instead, repeated total bilirubin measurement is used to determine the rate of increase of serum bilirubin concentrations to determine the need for institution of phototherapy or exchange transfusion to reduce serum bilirubin levels. Under some circumstances, the measurement of covalently albumin-bound ...
It is essential to further investigate novel risk factors for CVD and to look for potential ways to reduce the burden of CVD in T2DM. In this regard, high uric acid levels and low bilirubin concentrations were observed to be associated with CVD8,9. Uric acid is a metabolic end product of...