(1991) Fi- brosis of the liver in rats induced by bile duct ligation. Effects of inhibi- tion of prolyl 4-hydroxylase. J. Hepatol. 13, S35-S40.Boker, K., Schwarting, G., Kaule, G., Gunzler, V. & Schmidt, E. Fibrosis of the liver in rats induced by bile duct ligation. ...
Hepatic fibrosis is a common outcome of a variety of chronic liver diseases. Here we evaluated the therapeutic efficacy of hepatocyte growth factor (HGF) on liver fibrosis induced by bile duct ligation (BDL) and investigated potential mechanisms. Mice underwent BDL, followed by intravenous injections...
The present study was undertaken to clarify whether methanolic extract of Tridax procumbens prevents liver fibrosis in rat. The hepatic fibrosis was induced by 28 days of bile duct ligation in rats. The 4-week treatment with Tridex procumbens reduced the serum aspartate aminotransferase (U L−...
Effect of (Linn.) on bile duct ligation-induced liver fibrosis in ratsP.T. DeshmukhJoshi PP, Patil SD, Silawat N, Deshmukh PT. Effect of Tridax procumbens (Linn.) on bile duct ligation-induced liver fibrosis in rats. Nat Prod Res 2011;25:1975-81....
Liver slides were stained by hematoxylin and eosin and Masson trichrome\Gomory reticulum staining. Aspartate aminotransferase(AST) and alkaline phosphatase levels in the BDL + NAC group were lower t 展开 关键词: Antifibrotic N-acetylcysteine Bile duct ligation Hepatic fibrosis Rat ...
A mouse experiment shows that Oct3 deletion enhances liver fibrosis by thioacetamide (TAA) and bile duct ligation (BDL)4. Feeding with a high-fat diet increases gentamicin-induced nephrotoxicity due to higher accumulation of gentamicin by induction of renal Oct2 expressions5. On the contrast, Oct...
Despite alterations in gut microbiota in CLD, the specific mechanisms of how gut microbiota dysbiosis promotes liver fibrosis are still under exploration. Zhou et al. (2023) confirmed that the depletion of gut microbiota exacerbated cholestatic liver injury in mice under bile duct ligation (BDL). ...
Moreover, treatment with telmisartan significantly increased the expression levels of ACE2 and MAS proteins, and inhibited the expression levels of ACE and AT1-R protein.Telmisartan attenuates liver fibrosis in bile duct-ligated rats via increasing ACE2 expression level. 展开 关键词:...
In the present study, we investigated the effects of pantoprazole (PPZ), a PPI, against liver fibrosis in a bile duct ligation (BDL) rat model, human hepatic stellate cell (HSC) line LX-2 and mouse primary HSCs (pHSCs), and explored the potential mechanisms underlying the effects of PPZ...
Telmisartan attenuates liver fibrosis in bile duct-ligated rats via increasing ACE2 expression level. This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 251,40 € per year only 20,95 € per...