The observed liver injury by Ad-BCL2 was unlikely attributed by the mild inflammation by adenovirus, as it was not observed with the AdGFP-control. A revolution in the analysis of RNA has come through the development of deep sequencing (RNA-seq) tech- nologies to map the entire ...
FAMILIAL NEONATAL HEPATITIS WITH UNUSUAL CHOLANOID METABOLISM 427 y had been accompanied by a deterioration in liver histology; there was an established cirrhosis with cholestasis and active (although reduced) portal inflammation. Pruritus remained a problem, and rifampicin (10 mglkgld) was added to ...
The underlying convergent mechanism for these cancers may be chronic inflammation lasting for decades and thus offering possibilities for intervention and disease monitoring. Keywords: hepatocellular carcinoma; comorbidity; risk factor; bile duct infection; alcohol; viral infection...
Gallstone disease causes chronic inflammation which has the strongest correlation with gallbladder malignancy [4]. Gallbladder and bile duct tissues accumulate genetic mutations which can lead to malignancy formation. The most known mutation is in the TP53 tumor suppressor gene [5]. Other risk ...
From dried bear bile to molecular investigation: A systematic review of the effect of bile acids on cell apoptosis, oxidative stress and inflammation in the brain, across pre-clinical models of neurological, neurodegenerative and neuropsychiatric disorders. Brain Behav. Immun. 2022, 99, 132–146. ...