In the present work, analysis of the hypolipidemic properties of Trachinotus ovatus protein hydrolysates (TOPHs) and identification of peptides with bile acid-binding activity were performed. Hydrolysates prepared by trypsin digestion exhibited the highest in vitro bile acid-binding capacities compared wit...
Geniposide also down-regulated expression of Farnesoid X receptor (FXR), small heterodimer partner (SHP) and bile salt export pump (BSEP). In conclusion, 300 mg/kg Geniposide can induce liver injury with associated changes in bile acid regulating genes, leading to an accumulation of taurine co...
On the contrary, a recent study indicated that BA (TUDCA) supplements could improve recovery in mice from the 5-FU treatment [257]. It is currently not well established how intricate the bile acid/chemotherapy axis is in PC. Although we have discussed the involvement of BAs in pathogenesis,...
These studies suggest that bile acid interactions with other plant compounds, such as proteins and phytochemicals, may add to the bile acid retarding effects of dietary fibres [16]. The objective of this review is to provide an update on the most recent findings concerning bile acid interactions...
Firstly, the dogs used in this study were client-owned and were fed different habitual diets that could have resulted in a potential confounding factor in the assessment of the effects exerted by the HCD treatment on the fecal microbiota, sterol, and fatty acid profile of CE dogs. In ...