ICE Pharma offers an extensive portfolio of products and services for the pharmaceutical and healthcare markets. We have a unique range of bile acid products and are a leading global integrated producer of Ursodeoxycholic acid (UDCA). View our Products rangeView our Services Introducing our bile a...
ICE Pharma is an expert in the development and manufacture of bile acid derivatives. We are a leading producer of Ursodeoxycholic Acid (UDCA) with an integrated global manufacturing network in Europe, Latin America, Asia and Oceania that serves customers in over 50 countries. Our five R&D centres...
Urinary bile acids are also present mainly in conjugated form, and only a few milligrams per day are excreted. However, in hepatobiliary diseases like primary biliary cirrhosis, urine may become a major pathway for bile acid excretion and sulfate conjugation of bile acids is increased. Again, ...
Bile acid Chronic metabolic disease Gut microbiota FXR Metabolic regulation 1. Introduction Bile acids (BA), resulting from the breakdown of cholesterol in the liver [1], play a role in regulating various bodily functions, both in the liver and other tissues. They also serve as regulators for ...
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A separate culture of mCherry-SV40SM was subjected to 1 μM γ-aminobutyric acid (GABA) for 7 days to induce expression of large cholangiocyte proteins60. Apical transport of cholyl-lysyl-fluorescein (CLF) was examined by incubating GABA-mCherry cells in 5 μM CLF dissolved in HBSS ...
ICE Pharma are experts in the development and manufacture of bile acid derivatives and are a leading producer of Ursodeoxycholic Acid (UDCA).