ICE Pharma offers an extensive portfolio of products and services for the pharmaceutical and healthcare markets. We have a unique range of bile acid products and are a leading global integrated producer of Ursodeoxycholic acid (UDCA). View our Products rangeView our Services ICE Pharma has develope...
While the three-dimensional (3D) structure of NAAA is still unknown, the crystallographic coordinates of a choloylglycine hydrolase prototype, namely conjugatebile acidhydrolase (CBAH;Rossocha, Schultz-Heienbrok, von Moeller, Coleman, & Saenger, 2005), have been recently resolved and used to buil...
Bile acid Chronic metabolic disease Gut microbiota FXR Metabolic regulation 1. Introduction Bile acids (BA), resulting from the breakdown of cholesterol in the liver [1], play a role in regulating various bodily functions, both in the liver and other tissues. They also serve as regulators for ...
ICE Pharma offers an extensive portfolio of products and services for the pharmaceutical and healthcare markets. We have a unique range of bile acid products and are a leading global integrated producer of Ursodeoxycholic acid (UDCA). View our Products rangeView our Services ICE Pharma has develope...
Functions as a peptidyl-prolyl cis–trans isomerase 0.9 Peptidase family M23 0.2 Cleaves the N-terminal amino acid of tripeptides 3.2 Peptidase dimerisation domain −0.7 Aminopeptidase P, N-terminal domain 0.8 Belongs to the cytidylate kinase family. Type 1 subfamily −2.0 Catalyzes the ...
A separate culture of mCherry-SV40SM was subjected to 1 μM γ-aminobutyric acid (GABA) for 7 days to induce expression of large cholangiocyte proteins60. Apical transport of cholyl-lysyl-fluorescein (CLF) was examined by incubating GABA-mCherry cells in 5 μM CLF dissolved in HBSS ...
These findings indicate that FGF15/19 could be a critical factor for liver size control. However, the mechanisms underlying bile acid-mediated liver growth and size control remain largely unknown. In the present study, we demonstrate that in response to increased amounts of intestinal bile, ...