Although colesevelam has a cleaner drug interaction profile than other bile acid sequestrants, it does interfere with absorption of some drugs. A 4-hour window appears sufficient to eliminate these interactions.Dr Karen S. Brown PhDDaiichi Sankyo Pharma DevelopmentMs Ingrid C. Armstrong MS...
Bile acid sequestrants are not absorbed into the body, and therefore they do not have systemic side effects (affecting other organs). Their most common side effects are gastrointestinal and these include constipation, abdominal pain, bloating, vomiting, diarrhea, weight loss, excessive passage of ...
网络释义 1. 胆汁酸螯合剂 英汉词汇_地道... ... bilateral ventricular hypertrophy 双侧心室肥大 bile-acid sequestrant 胆汁酸螯合剂 bile duct 胆管 ... hi.baidu.com|基于7个网页© 2025 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈
Define Bile acid sequestrant. Bile acid sequestrant synonyms, Bile acid sequestrant pronunciation, Bile acid sequestrant translation, English dictionary definition of Bile acid sequestrant. n. A chemical that promotes sequestration. American Heritage®
Bile acid sequestrants bind bile acids in the intestine and their complexes with bile acids are non-absorbable and not easily destroyed. As a result, bile acid sequestration induces feedback regulation of bile acid synthesis by inhibiting intestinal FXR-FGF15 signaling and allowing the conversion of...
Pharmaceutical composition containing bile acid sequestrant enclosed in a size-exclusion membraneUS5091175 * May 14, 1990 Feb 25, 1992 Erbamont Inc. Pharmaceutical composition containing bile acid sequestrant enclosed in a size-exclusion membrane...
Ezetimibe and bile acid sequestrants are both effective agents for reducing LDL-C, either used alone or in combination with statins. The statins, fibric ... Dr,Peter,P.,... - 《Drugs》 被引量: 146发表: 2010年 Dietary Phylloquinone and Menaquinones Intakes and Risk of Type 2 Diabetes bi...
Furthermore, the administration of bile acid sequestrants has been shown to slow the progression of diabetic kidney disease in rats [103]. There is compelling evidence to suggest the importance of gut microbiota and bile acids in the regulation of metabolic processes, fundamentally influencing the ...
increased Side effects huge GI problems don't give in ppl with TG >300 Welchol dosing 3BID or 6 at one time Really only prescribed if intolerance to Zetia These drugs must be administered With food and liquid How to we reduce constipation in this class Fruits fibers stool softener关于...
2.5. Effects of interrupting the enterohepatic circulation of bile acids (Fig. 2) Bile acids physiologically undergo enterohepatic circulation (see Introduction). Bile acid sequestrants such as cholestyramine or bile acid re-uptake inhibitors such as ASBT inhibitors interrupt the enterohepatic circulation ...