Suhr O, Danielsson A, Steen L (1992) Bile acid malabsorption caused by gastrointestinal motility dysfunction? an investigation of gastrointestinal disturbances in familial amyloidosis with polyneuropathy. Scand J Gastroenterol 27:201-207Suhr O, Danielsson A, Steen L. Bile acid malabsorption caused by ...
Primary bile acid malabsorption (PBAM) is an idiopathic intestinal disorder associated with congenital diarrhea, steatorrhea, interruption of the enterohep... P Oelkers,LC Kirby,JE Heubi,... - 《Journal of Clinical Investigation》 被引量: 1020发表: 1997年 Role of bile acid malabsorption in path...
Bile acid malabsorption(BAM) results from the interruption of the recirculation of bile acids through the enterohepatic circulation (increased biosynthesis or secretion of bile acids, or malabsorption in the ileum), leading to their excessive loss into the colon where they cause diarrhea by stimulating...
SeHCAT [tauroselcholic (selenium-75) acid] for the investigation of bile acid malabsorption and measurement of bile acid pool loss: a systematic review and... Background: The principal diagnosis/indication for this assessment is chronic diarrhoea due to bile acid malabsorption (BAM). Diarrhoea ca...
BAD may be due to malabsorption or overproduction of BAs. The ileal hormone fibroblast growth factor 19 (FGF19) regulates hepatic BA synthesis and is low in BAD4. Bile acids undergo an enterohepatic circulation. Less than 5% of the glycine- and taurine-conjugated primary BAs, cholic acid (CA...
- 《Journal of Clinical Investigation》 被引量: 308发表: 2012年 Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Familial hypercholanemia (FHC) is characterized by elevated serum bile acid concentrations, itching, and fat malabsorption[SUP1,2]. We show ...
195 Similarly in humans, inherited mutations in ASBT cause significant bile acid malabsorption.196 The general consensus from these studies was that ileal active transport is the major route for conjugated bile acid uptake, whereas passive or facilitative absorption down the length of the small ...
As a result a rational basis for treatment has been made possible, for example the dissolution of cholesterol gallstones with chenodeoxycholic acid and ursodeoxycholic acid or the treatment of bile acid malabsorption syndromes with cholestyramine and medium-chain triglycerides. However, despite the ...
Articles Translational Investigation nature publishing group Dietary fish oil increases fat absorption and fecal bile acid content without altering bile acid synthesis in 20-d-old weanling rats following massive ileocecal resection Qing Yang1, Tian Lan2,3, Yuegang Chen1 and Paul A. Dawson2...
Christiaens H, Leer RJ, Pouwels PH, Verstraete W (1992) Cloning and expression of a conjugated bile acid hydrolase gene from Lactobacillus plantarum by using a direct plate assay. Appl Environ Microbiol 58:3792–3798. https://doi.org/10.1128/aem.58.12.3792-3798.1992 Article CAS PubMed PubMed...