& ROTH, J. Enzyme Evolution: Generation of a Bifunctional Enzyme by Fusion of Adjacent Genes. Nature 228, 820–824 (1970). https://doi.org/10.1038/228820a0 Download citation Received29 June 1970 Revised01 October 1970 Issue Date28 November 1970 DOIhttps://doi.org/10.1038/228820a0 Springer...
When isolated, the bifunctional enzyme promotes production of more molecules of the robust species while when bound, the same enzyme facilitates degradation of the robust species. These dual actions produce robustness in the large class of covalent modification networks. For each network of...
The bifunctional enzyme achieved xylose and arabinose co-production from natural biomass. This study provides a new strategy for the utilization of agricultural waste. Introduction Industrial development has been the major cause of energy shortages and associated environmental pollution [1]. To alleviate ...
Prostaglandin-H-synthase (PGHS, EC 1.14.99.1) catalyzes the first committed step in biosynthesis of all prostaglandins, thromboxanes, and prostacyclins by converting arachidonic acid to prostaglandin H2 (PGH2). PGHS exhibits two enzymatic activities: cyclooxygenase activity convertin...
Properties and regulation of the bifunctional enzyme HPr kinase/phosphatase in Bacillus subtilis. J. Biol. Chem. 278:1174-1185.Ramstrom, H., Sanglier, S., Leize-Wagner, E., Philippe, C., Van Dorsselaer, A. and Haiech, J. (2002) Properties and regulation of the bifunctional enzyme HPr...
Peroxisomal bifunctional enzyme binds and activates the activation function-1 region of the peroxisome proliferator-activated receptor alpha Meier CA (2001) Peroxisomal bifunctional enzyme binds and activates the activation function-1 region of the peroxisome proliferator-activated receptor alpha. Bi... CE...
Preparation of a soluble bifunctional enzyme by gene fusion. Nat Biotechnol 1985;3:821-3.Bülow L, Ljungcrantz P, Mosbach K (1985) Preparation of a soluble bifunctional enzyme by gene fusion. Biotechnology 3:821–823 View ArticleBulow L, Ljungcrantz P, Mosbach K (1985) Preparation of a ...
The bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase catalyzes both the synthesis and degradation of fructose-2,6-bisphosphate, a potent regulator of glycolysis. Thus this bifunctional enzyme plays an indirect yet key role in the regulation of glucose metabolism. RESULTS: We ...