Leading Article: An Environmental Court Could Protect Us from the Bias of PoliticiansTHE GOVERNMENT prides itself on its ability to listen. All too often, however, it seems determined not to do so. As reported in The Independent today, Lord Woolf, the Lord Chief Justice, has called for an ...
To date, most preclinical biomedical research has been conducted with inadequate consideration of the sex of the experimental subjects studied16,17,18. In the current article, we are focusing on the experimental animal maternal immune activation (MIA) model to exemplarily illustrate the current state...
Article pubs.acs.org/biochemistry Principles for Understanding the Accuracy of SHAPE-Directed RNA Structure Modeling Accurate RNA structure modeling is an important, incompletely solved, challenge. Single-nucleotide resolution SHAPE (selective 2鈥hydroxyl acylation analyzed by primer extension) yields an ...
An article today, written by Frances Robles, has nearly 1700 words on how the national economy is a mess and how one town has been devastated, yet nary a word about the policies that caused the downfall. It was once a thriving metropolis in the heart of oil country in Venezuela. That ...
An underdeveloped research line consists of rejecting the low-confidence outputs of an AI system in favor of escalating the decisions to a human agent who could possibly take into account additional (qualitative) information. This is considered in the area of classification with areject option(orsel...
Share article on Twitter Share article on Facebook You want to believe that you’re inclusive and open-minded. That you celebrate people’s differences. That you’re respectful of alternative beliefs and ideas. That you’re accepting of everybody’s backgrounds and experiences. ...
During an April 2016 presentation in Japan, he noted that plant operators at TMI and Fukushima each relied on instruments that falsely indicated “that there was a lot of water in the nuclear reactor, when in fact there was none.” He went on to say: “Every reading that was true and ...
Article30 November 2023 Introduction Genome-wide association studies (GWASs) have reported hundreds of thousands of associations between single-nucleotide polymorphisms (SNPs) and various phenotypes1, but most reported SNPs reside in non-coding regions2,3,4. As the cell type and cellular process in...
We discuss the implications of mutational bias as an evolutionary driver in other cis-regulatory systems.Similar content being viewed by others Alternative splicing modulation by G-quadruplexes Article Open access 03 May 2022 The intronic branch point sequence is under strong evolutionary constraint ...
Article 16 March 2021 Introduction Organic synthesis remains a challenge in small molecule drug design, sinking time in the design-make-test cycle and potentially limiting the complexity of chemical space being explored1,2. The challenge of synthesis planning lies in searching through myriad of possib...