ItissaidthatThomasEdisonusedtochasethetwilight(追求模糊状态)momentsbetweenwakefulnessandsleep.Supposedly,heusedtofallasleepinachair,holdingtwoballsinhishands.Ashenoddedoff,theballsfelldown.Theresultingnoisewokehimup.Then,hecouldwritedownhisinventiveideasbeforehefellintoadeepsleepandforgotthem.Thisinspiredanewstudy...
阅读理解It is said that Thomas Edison used to chase the twilight(黄昏) moments between wakefulness and sleep. He used to fall asleep in a chair, holding two steel balls in his hands. As he nodded off, the balls fell into metal pans. The resulting clatter woke him up. Then, he could ...
Physiology Age-related changes in sleep EEG and transitions between wakefulness and sleep states UNIVERSITY OF COLORADO AT BOULDER Kenneth P. Wright ChinoyEvan DavidSleep is altered by the aging process. Not only are the prevalence of sleep disorders and sleep complaints increased with age, notably,...
After 10 min, ∼50% of the subjects had at least one epoch of sleep. (B) Probability of subjects being awake and in the different NREM sleep stages (N1, N2, and N3 sleep) as a function of time. (C) Total time spent by the subjects in wakefulness and all NREM sleep stages. ...
ERK signaling pathway regulates sleep duration through activity-induced gene expression during wakefulness. Sci. Signal. 10, eaai9219 (2017). PubMed Google Scholar Hendricks, J. C. et al. A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis. Nat. Neurosci....
For many people, the cruelest part of daily life is the transition between wakefulness and sleep. When you should be sleeping, you want to be awake; when you should be awake, you want to stay asleep. It is easy to regard sleep as a toment; hard to altain and then hard to give up...
For many people, the cruelest part of daily life is the transition between wakefulness and sleep. When you should be sleeping, you want to be awake; when you should be awake, you want to stay asleep. It is easy to regard sleep as a torment: hard to attain and then hard to give up...
The phosphorylation of synaptic proteins is a significant biochemical reaction that controls the sleep–wake cycle in mammals1–3. Protein phosphorylation in vivo is reversibly regulated by kinases and phosphatases. In this study, we investigate a pair o
Instability in the sleep/wake cycle can be attributed to the lack of orexin, which plays a crucial role in regulating the transitions between wakefulness and sleep [10]. These studies have identified increased sleep disruption in children with NT1 compared to a combined group of children with ...
EPA group had a significant decrease in total time in bed and total sleep time. The authors identified EPA’s unique role as a sleep-supporter by inhibiting the formation of E2-series prostaglandins, which in turn inhibits the release of serotonin, a neurotransmitter associated with wa...