By means of a pseudoreceptor modeling approach, we have developed a binding site model for a series of taxanes. It is the first 3D QSAR model derived from the experimentally determined tubulin structure obtained by electron crystallography studies. The model is able to correlate quantitatively the ...
DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43 M.The negative control (inset) is a secondary-only assay to demonstrate low non-specific binding of the secondary antibody.This product also gave a positive signal under the same testing conditions in HeLa cells fixed ...
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Define beta-tubulin. beta-tubulin synonyms, beta-tubulin pronunciation, beta-tubulin translation, English dictionary definition of beta-tubulin. n. A globular protein that is the basic structural constituent of microtubules. American Heritage® Diction
Tubulin-tyrosine ligase has a binding site on beta-tubulin: a two-domain structure of the enzyme. J. Cell Biol. 1987; 104:1059-1067. [PubMed: ... J,Wehland,K,... - 《Journal of Cell Biology》 被引量: 103发表: 1987年 Structure of the alpha beta tubulin dimer by electron crystallo...
The tubulin-binding protein gephyrin copurifies with the inhibitory glycine receptor (GIyR) and is essential for its postsynaptic localization. Here we have analyzed the interaction between the GIyR and recombinant gephyrin and identifie...
The -tubulins are microtubule components encoded by a multigene family, which produces slightly different proteins with complex expression patterns. Several widely used anticancer drugs base their activity on -tubulin binding, microtubule dynamics alteration, and cell division blockage. The expression of ...
货号MA1-19164 100 µg CNY4,885.00 查看价格 下单后预计有货时间 14-Jan-2025 数量 批量或定制请求 性能保障 说明书 实验方案 技术支持 Application Created with Sketch. 图:1/6 beta Tubulin Antibody (MA1-19164) in ICC/IF Immunocytochemistry staining of 3T3 mouse embryonal fibroblast cell line using...
Sf9 β-tubulin interacts with Arnt and suppresses the binding of the AhR/Arnt heterodimer to its corresponding enhancer. Human β4-tubulin, which shares high sequence identity with Sf9 β-tubulin, suppresses the AhR-dependent luciferase expression by reducing the nuclear Arnt content and retaining ...
BZ resistance was associated with a decrease in high-affinity BZ binding to tubulin and an alteration in β-tubulin isoform pattern. 展开 关键词: pesticide resistance, Haemonchus contortus, specific binding, tubulin, high-affinity binding, benzimidazoles, sheep DOI: 10.1016/0166-6851(91)90155-Y ...