Singh, Identification of group specific motifs in beta- lactamase family of proteins. J Biomed Sci, 2009. 16: p. 109.Singh R, Saxena A, Singh H. Identification of group specific mo- tifs in beta-lactamase family of proteins. J Biomed Sci. 2009;16:109. doi: 10.1186/1423-0127-16-109...
All the enzymes reported and characterised in the literature are presented according to the class (A, B, C and D), family and subfamily to which they belong. All three-dimensional structures of -lactamases present in the Protein Data Bank are also shown. The characterisation of representative ...
(ESBLs) andcarbapenemasessuch as the KPC family and the VIM, IMP, and NDM metallo-enzymes [14,15]. These beta-lactamases are now appearing in multiple combinations of ESBLs and carbapenemases, thereby conferring resistance to virtually all beta-lactam antibiotics [16•]. The acquisition of ...
BlaA belongs to the LysR family of transcription activators, whereas BlaB shares some features with the penicillin-recognizing proteins. BlaB has now been overexpressed in Escherichia coli, purified and used for antibody preparation. Immunoblotting of cell-fractionated materials from S. cacaoi showed ...
The family of TEM β-lactamases disseminated worldwide through various Enterobacteriaceae, as well as Pseudomonas aeruginosa, Haemophilus influenzae, and N. gonorrhoeae.46,47 Similarly, both chromosomally encoded, as well as plasmid-mediated SHV-type β-lactamases, with a molecular s...
Funding for this project was provided through the Health Studies Fund of the University of Utah Department of Family and Preventive Medicine and through internal University Seed Funding. We are grateful for the outreach efforts of Sarah Wright and the Association of Public Health Laboratories (APHL)...
YbxI belongs to the penicillin-recognizing enzyme family but has an activity intermediate between those of a penicillin-binding protein and a beta-lactamase. 展开 关键词: Bacillus subtilis ßLactamase Activity DOI: 10.1128/AAC.48.2.484-490.2004 ...
The highly conserved 14-3-3 protein family has risen to a position of importance in cell biology owing to its involvement in vital cellular processes, such... DK Morrison - 《Trends in Cell Biology》 被引量: 929发表: 2009年 TEM-72, a new extended-spectrum beta-lactamase detected in Prote...
The prototype for the Ambler type D beta-lactamases is the OXA family of beta-lactamases. OXA beta-lactamase is so designated because it has a higher rate of hydrolysis for oxacillin compared to benzylpenicillin.63 A number of OXA enzymes exhibit carbapenemase activity, although this may not co...
Since it is a LysR-type transcription factor (LTTR) family protein, AmpR has a winged helix-turn-helix DNA binding domain (HTH-DBD) at the N-terminus (residues 8–66) and an effector binding domain (EBD) at the C-terminus (residues 95–268). The HTH-DBDs were 100% identical between...