Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
Type 3 hemochromatosis and beta-thalassemia trait. Alessia Riva,Raffaella Mariani,Giorgio Bovo,Sara Pelucchi,Cristina Arosio,Alessandra Salvioni,Anna Vergani,Alberto Piperno<. European Journal of Haematology . 2004Riva Al,Mariani, Rl,,Bovo, G2,et al.Type 3 hemochromatosis and [beta]-thalassemia ...
Deferiprone in the treatment of transfusion-dependent thalassemia: a review and perspective. Ther Clin Risk Manag 2007; 3: 795–805. CAS PubMed PubMed Central Google Scholar Neufeld EJ . Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, ...
only about 200,000 patients with thalassemia major are alive and registered as receiving regular treatment around the world [3]. The most common combination of beta-thalassemia
Antenatal screening for beta thalassemia trait (BTT) followed by counseling of couples is an efficient way of thalassemia control. Since high performance liquid chromatography (HPLC) is costly, other cost-effective screening methods need to be devised for this purpose. The present study was aimed ...
Adults in a health maintenance organization, unselected for interest, were screened for beta-thalassemia trait as part of preventive health care. Counseling was provided by either a trained physician (conventional counseling) or by a videotape containing the same information followed by an opportunity ...
1. “Thalassemia Beta” By National Heart Lung and Blood Institute (NIH) – National Heart Lung and Blood Institute (NIH) (Public Domain) via Commons Wikimedia 2. “B Thalassaemia Trait (Basophilic Stippling)” By Dr Erhabor Osaro – Own work(CC BY-SA 3.0)via Commons Wikimedia...
- Thalassemia trait (BTT) in a medical students of Karachi, Pakistan and to confirm the validity of Naked Eye Single Tube Red cell Osmotic Fragility Test (NESTROFT) to qualify for a mass screening test for BTT detection. SETTING: An analytical cross sectional study, performed from Jan 2010 ...
Affected individuals have a different mutation in each copy of their HbB gene; one gene causes the cells to become sickled and the other is associated with β-thalassemia, a blood disorder that reduces the production of hemoglobin [1]. There is a 1:4 chance of having a child with Sβ-...
Thalassemia major is one of the most common genetic disorders in Pakistan and over five thousand new patients are added in the pool annually. This familial disease has both medical and social implications, and therefore there is a need to assess the magnitude of beta-Thalassemia trait amongst fam...