Beta thalassemia trait ranks second to iron deficiency as the most frequent cause of anemia of pregnancy in our clinic. The anemia of patients with thalassemia trait increases during the second trimester, as does that with normal controls. This is not sufficient to result in any disability or ...
Persons with thalassemia minor have (at most) mild anemia (slight lowering of the hemoglobin level in the blood). This situation can very closely resemble that of mild iron deficiency anemia. However, persons with thalassemia minor have a normal blood iron level (unless they are iron deficient ...
Beta-thalassemia is caused by the reduced (beta+) or absent (beta0) synthesis of the beta globin chains of the hemoglobin tetramer. Three clinical and hematological conditions of increasing severity are recognized, i.e., the beta-thalassemia carrier state, thalassemia intermedia, and thalassemia ma...
variably referred to as "Cooley's Anemia" and "Mediterranean Anemia", Thalassemia Intermedia and Thalassemia Minor also called "beta-thalassemia carrier", "beta-thalassemia trait" or "heterozygous beta-thalassemia". Apart from the rare dominant...
Because of chronic anemia, hypogonadotropic hypogonadism, and iron chelation, pregnancy in homozygous and heterozygous compound beta-thalassemia patients s
REBLOZYL® (luspatercept-aamt) is a prescription medicine used to treat patients with anemia in myelodysplastic syndromes (MDS) & anemia in beta thalassemia (BT). Please see Indication and Important Safety Information.
A European panel has recommended approval of luspatercept for the treatment of anemia in patients with myelodysplastic syndromes and beta thalassemia.
Patients who are heterozygous (one normal β-globin gene and one mutant β-globin) have more moderate anemia and produce enough β-globin chains to obviate the need for ongoing transfusions—referred to as β-thalassemia trait, or β-thalassemia minor. In patients with thalassemia, the issues...
Related to Beta thalassemia:Alpha Thalassemia thal·as·se·mi·a (thăl′ə-sē′mē-ə) n. An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule. Also calledMediterranean anemia. ...
Related to Beta thalassaemia:thalassemia major,Thalassemia intermedia,Thalassemia minor thal·as·se·mi·a (thăl′ə-sē′mē-ə) n. An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule. Also called...