The reason that the gene for beta thalassemia is relatively common, for example, among people of Italian and Greek origin is that parts of Italy and Greece were once full ofmalaria. The presence of thalassemia minor (like the sickle cell trait in Africa) afforded protection against malaria, an...
The reason that the gene for beta thalassemia is relatively common, for example, among people of Italian and Greek origin is that parts of Italy and Greece were once full ofmalaria. The presence of thalassemia minor (like the sickle cell trait in Africa) afforded protection against malaria, an...
Thalassemia major is one of the most common genetic disorders in Pakistan and over five thousand new patients are added in the pool annually. This familial disease has both medical and social implications, and therefore there is a need to assess the magnitude of beta-Thalassemia trait amongst fam...
A screening test for beta-thalassemia trait carriers is carried out by mixing 10 &mgr;l of blood of the patient with 2 ml of an aqueous solution prepared from glycerol, sodium chloride, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium azide, Acid Green 5 to obtain a suspension...
Six subjects in the first group and 13 in the second were found to be carriers of the beta-thalassemia trait. Statistical analysis of the data did not show any significant difference between the two groups. It seems that the beta-thalassemia trait does not provide any protection against ...
Sickle Cell Beta Thalassemia is a condition characterized by the inheritance of one β S gene and a thalassemia defect on the other β gene, resulting in variable amounts of protein production and similarities to sickle cell anemia in hematology and prognosis. ...
Patients who are heterozygous (one normal β-globin gene and one mutant β-globin) have more moderate anemia and produce enough β-globin chains to obviate the need for ongoing transfusions—referred to as β-thalassemia trait, or β-thalassemia minor. In patients with thalassemia, the issues...
It was found that 2.3% of the participants are the carriers of β thalassemia, 1.3% are the carriers of the sickle cell trait. There were not significant relationship between the disease frequencies and the sexes. CO N C L U S I O N S A cc o rding to the data of the Ministry of...
The two most frequent types of microcytic anemia are beta thalassemia trait (β-TT) and iron deficiency anemia (IDA). We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis ... A Vehapoglu,G Ozgurhan,AD Demir,... - 《Anemia》 被引量: 51...
relates to the mentioned nucleic acid molecules wherein a panel of 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 or 14 of the polymorphic, changed sequences comprising the mentioned indicator nucleotides constitutes a marker for beta thalassemia, in particular of beta thalassemia minor....