Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
Sharifian, “Is Beta-Thalassemia Trait a Protective Factor against Hypertension in Young Adults?” Ann Hematol, Vol. 85, No. 1, January 2006, pp. 29-31.Karimi M, Marvasti VE, Motazedian S, et al. Is beta-thalassemia trait a protective factor against hypertension in young adults? Ann ...
Because total cholesterol levels have been found to be lower in patients affected by thalassemia major and intermedia, we examined the plasma lipid pattern of 628 beta-thalassemia trait carriers and 4552 controls in order to evaluate whether the plasma lipid impairment is also present in the heteroz...
Related to Beta thalassemia:Alpha Thalassemia thal·as·se·mi·a (thăl′ə-sē′mē-ə) n. An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule. Also calledMediterranean anemia. ...
Beta thalassemia traitMachine learning algorithmAntenatal screening for beta thalassemia trait (BTT) followed by counseling of couples is an efficient way of thalassemia control. Since high performance liquid chromatography (HPLC) is costly, other cost-effective screening methods need to be devised for ...
Premarital screening of beta-thalassemia trait in the province of Denizli, Turkey. Acta Haematol 2000; 104(1):31-3.Keskin A, Turk T, Polat A, Koyuncu H, Saracoglu B. Premarital screening of beta- thalassemia trait in the province of Denizli, Turkey. Acta Haematol 2000;104:31-33....
Beta-thalassemia associated with other features In rare instances the beta-thalassemia defect does not lie in the beta globin gene cluster. In cases in which the beta-thalassemia trait is associated with other features, the molecular lesion has been found either in the gene encoding the transcripti...
Related to Beta thalassaemia:thalassemia major,Thalassemia intermedia,Thalassemia minor thal·as·se·mi·a (thăl′ə-sē′mē-ə) n. An inherited form of anemia occurring chiefly among people of Mediterranean descent, caused by faulty synthesis of part of the hemoglobin molecule. Also called...
thalassemia may affect one or both of the beta-globin genes (HBB gene). Beta thalassemia has three main types: minor, intermediate, and major. Beta-thalassemia major (Cooley’s anemia) and beta-thalassemia intermediate are severe forms, whereas beta-thalassemia minor is a mild form of this ...
Beta-thalassemia is caused by the reduced (beta+) or absent (beta0) synthesis of the beta globin chains of the hemoglobin tetramer. Three clinical and hematological conditions of increasing severity are recognized, i.e., the beta-thalassemia carrier state, thalassemia intermedia, and thalassemia ma...