Beta thalassemia trait ranks second to iron deficiency as the most frequent cause of anemia of pregnancy in our clinic. The anemia of patients with thalassemia trait increases during the second trimester, as does that with normal controls. This is not sufficient to result in any disability or ...
The term thalassemia is derived from the Greek, thalassa (sea) and haima (blood). Beta-thalassemia includes three main forms: Thalassemia Major, variably referred to as "Cooley's Anemia" and "Mediterranean Anemia", Thalassemia Intermedia and Thalassemia Minor also called "beta-thalassemia carrier",...
Beta-thalassemia is caused by the reduced (beta+) or absent (beta0) synthesis of the beta globin chains of the hemoglobin tetramer. Three clinical and hematological conditions of increasing severity are recognized, i.e., the beta-thalassemia carrier state, thalassemia intermedia, and thalassemia ma...
Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
β-Thalassemia is the most common autosomal recessive single-gene disorder in Sardinia, where approximately 10.3% (1 out of 9 people) of the population is a carrier. The HBB c.118C4T variant (rs11549407), better known as the nonsense β°39 variant, is the most common variant, accounting...
Non-sustained ventricular tachycardia (NSVT) poses significant risks during pregnancy, particularly in patients with underlying conditions such as 尾-thalassemia. We present a case of a 29-year-old pregnant woman with a history of 尾-thalassemia minor who experienced NSVT at 27 weeks...
Diagnosis and clinical management of (beta)-Thalassemia minor in pregnancyM.A., ScharfP., BalanR.E., ScharfW., JanniR.E., Scharf
Differential diagnosis of Iron-deficiency anemia and Beta-Thalassemia, two common causes of anemia, affects the treatment in pregnant women. To help the diagnosis, we have tried to asses the pure effect of gestation on diagnostic criteria, eliminating iron and folate deficiency. In a prospective ...
Beta Thalassemia minor and its impact on glucose metabolism during pregnancy: a retrospective study to assess implication for mothers and offspringdoi:10.1055/s-0040-1713213Falcone, VReischer, TSpringer, SHusslein, P WRosta, KGeburtshilfe und Frauenheilkunde...
Objectives: To determine maternal and neonatal outcomes in pregnant women with betathalassemia minor in Kirkuk province, Iraq. Materials and methods: A case-control study was conducted and enrolled 95 pregnant women with beta-thalassemia minor and 100 control pregnant wo...