The transferases show absolute specificity for nucleotide A2058 in 23S rRNA; monomethylation at A2058 confers resistance to a subset of the macrolide, lincosamide, and streptogramin B (MLS(B)) group of antibiotics, dimethylation at A2058 confers high resistance to all MLS(B) and ketolide ...
In throat culture developed a beta-haemolytic Group A streptococci. We started a treatment by oral penicillin and in this way we obtained an absolute resolution of her symptoms. Four weeks later she had a further episode of facial tics associated with a confirmed streptococcal throat infection. ...