To probe the structural determinants in amyloid fibril formation, this thesis first describes the characterization of a combinatorial library of ) of individual protein molecules in the monolayers match those expected for proteins folded into amphiphilic β-sheets. The finding that similar structures are...
Beta-strand is a structural unit of protein beta sheets.This is an extended stretch of polypeptide chain typically 3 to 10 amino acids long that forms hydrogen bonds with other beta-strands in the same beta-sheet. beta-sheet(beta-折叠)是由几个beta-strand(beta-线串)组成的 (beta-strand 没...
protein synthesisthermal denaturationThe betabellin target structure consists of 2 32-residue beta sheets packed against each other by hydrophobic interactions. We have designed, chemically synthesized, and biophysically characterized betabellin 14S, a single chain, and betabellin 14D, the disulfide-...
Twitter Google Share on Facebook beta sheet (redirected fromBeta sheets) Medical Related to Beta sheets:Beta strand,Alpha helices beta sheet n. A secondary structure that occurs in many proteins and consists of two or more parallel adjacent polypeptide chains arranged in such a way that hydrogen...
Unexpectedly, the structures indicate that the intermediate-length fragments take helical conformations even though the full-length protein has no helical regions. The circular dichroism spectra and theoretical calculations also support the crystallographic results. This suggests that the short-range ...
Evolution of proteins formed by beta-sheets. I. Plastocyanin and azurinPseudomonas aeruginosaCopperBacterial ProteinsAzurinPlant ProteinsPlastocyaninProtein ConformationBinding SitesAmino Acid SequenceBiological EvolutionPlastocyanin and azurin form a family of small copper-containing proteins, active in the ...
-sheet protein The betabellin target structure consists of 2 32-residue beta sheets packed against each other by hydrophobic interactions. We have designed, chemically sy... Y Yan,BW Erickson - 《Protein Science》 被引量: 242发表: 1994年 Folding Free Energy Surface of a Three-Stranded β-...
protein foldingWe recently developed the Rosetta algorithm for ab initio protein structure prediction, which generates protein structures from fragment libraries using simulated annealing. The scoring function in this algorithm favors the assembly of strands into sheets. However, it does not discriminate ...
The primary structure of a protein is the amino acid sequence of the polypeptide chain. The way the polypeptide chain forms hydrogen bonds determines the secondary structure. There are two main types of secondary structures in proteins, alpha helices and beta pleated sheets. The hydrogen bonding pa...
Protein secondary structure: alpha-helices and beta-sheets, hairpins and loops, stabilization by hydrogen bonds