Our data further show, that SCPx, a 58 kDa protein with both thiolase and sterol carrier protein activity but unknown function so far, readily reacts with 3-oxopristanoyl-CoA. Taken together, our data show that SCPx plays a central role in branched chain fatty acid beta-oxidation in ...
(CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice Amit Kumar1,2, Joseph Shiloach1, Michael J Betenbaugh2 and Emily J Gallagher3* Abstract Background: The hallmark of Type 2 diabetes (T2D) is hyperglycemia, although there are multiple ...
L-bifunctional protein, and thiolase, and (b) a second noninducible pathway catalyzing the oxidation of 2-methyl-branched fatty acyl-CoAs by branched-chain acyl-CoA oxidase (pristanoyl-CoA oxidase/trihydroxycoprostanoyl-CoA oxidase), D-bifunctional protein, and sterol carrier protein (SCP)x. ...
P. (1996). Peroxisomal beta-oxidation of 2-methyl-branched acyl- CoA esters: stereospecific recognition of the 2S-methyl compounds by trihydroxycoprostanoyl-CoA oxidase and pristanoyl-CoA oxidase. FEBS Lett. 388, 80-84. doi: 10.1016/0014-5793(96)00508-X...
ACOX, acyl-CoA oxidasePCOX, pristanoyl-CoA oxidaseDespite increasing insight into peroxisomal 尾-oxidation, it is still not clear which enzymes catalyze very-long-chain fatty acid degradation. Using the northern blot and RT-PCR techniques, a brain-specific expression is demonstrated for acyl-CoA...
Pedersen, J.I., Veggan, T. and Bjorkhem, I. (1996) Substrate stereospecificity in oxidation of (25S)-3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoyl-CoA by peroxisomal trihydroxy-5 beta-cholestanoyl-CoA oxidase. Biochem. Biophys. Res. Commun., 224, 37-42....