influenzae isolated from 72 patients produced beta-lactamase and all of the beta-lactamase producing strains were isolated from patients with respiratory diseases. Of 6 strains serotyped by slide agglutination, 2 were type d, the remaining 4 were nontypable. All of the beta-lactamase producing H...
The resistance to betalactam antibiotics in a total of 177 clinical isolates of Haemophilus influenzae, mostly from respiratory tract samples and characterized by their betalactamase production, was studied using the cephalosporin chromogenic assay and by detecting bla(TEM) and bla(ROB) genes. A subst...
the first ESBL was described.26Certain beta-lactamases and ESBLs are genetically linked. As an example, the TEM-derived ESBL, the most common ESBL in gram-negative bacteria, differs from the parent TEM beta-lactamase by only 4 amino acids.27This small change confers the ability to hydrolyze ...
Soft-tissue infections of ampicillin-resistant Haemophilus influenzae type b. The use of ampicillin and nafcillin in their treatment. in treating five infants with soft-tissue infections and bacteremia due to beta-lactamase-producing, ampicillin-resistant Haemophilus influenzae type b. This... R Yogev...
Beta-Lactamase Inhibitors Sharon S.Castle, inxPharm: The Comprehensive Pharmacology Reference, 2007 Indications Empty CellValueUnitsPrep. and Route of Admin.ReferenceComments Infections caused by organisms producingbeta-lactamases. The beta-lactamase is always used in combination with a beta-lactam antimicr...
Beta lactamase resistance of newer cephalosporins and antimicrobial effectiveness against gram-negative bacilli Beta-Lactamase-Resistenz der neuen Cephalosporine und die antimikrobielle Wirksamkeit gegen gramnegative BazillenPublished: December 1977
Bergeron, M. G., Claveau, S., Simard, P.: Limited in vitro activity of cefamandole against 100 beta-lactamase- and non-beta-lactamase-producingHaemophilus influenzaestrains: Comparison of moxalactam, chloramphenicol, and ampicillin. Antimicrobial Agents and Chemotherapy 1981, 19: 101–105. ...
BROOK, I. Emergence and persistence of beta- lactamase-producing bacteria in the oropharynx following penicillin treatment. Arch Otolaryngol Head Neck Sur 114:667-70,1988.Brook. I.: Emergence and persistence of β-lactamase-producing bacteria in the oropharynx...
In respiratory tract infections Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae and Klebsiella spp. are the most frequently encountered bacterial pathogens. Resistance of clinical S. pneumoniae isolates is known to be independent of β-lactamase production, whereas resistance of the...
However, the low level of resistance of single cells makes it possible for ampicillin to cure some infections caused by β-lactamase–producing strains of H. influenzae when the initial inoculum of infecting bacteria is low. Another model is exemplified by ampicillin resistance of ...