beta-lactam antibiotic (redirected fromBeta-lactam antibiotics) Medical Encyclopedia Related to Beta-lactam antibiotics:beta-lactamase,Aminoglycosides n. Any of a class of broad-spectrum antibiotics, such as the penicillins and the cephalosporins, that contain a beta-lactam ring. ...
BETA-LACTAM COMPOUND, MANUFACTURE AND DRUGVinylcephalosporins of the formula (I) in which the symbols R<1>, R<2>, R<3>, R<4> and R<5> have the meaning given in the description.GUNTAA SHIYUMITSUTOKARURU GEORUKU METSUTSUGAAHANSUUYOAHIMU TSUAIRAARAINAA ENDAAMANINGO HARAA...
A list of attributes is also suggested for the description of a new beta-lactamase, including the requisite microbiological properties, substrate and inhibitor profiles, and molecular sequence data that provide an adequate characterization for a new beta-lactam-hydrolyzing enzyme. 展开 ...
Beta Lactamase TEM 1 is an enzyme encoded by the bla gene in E. coli, with its expression being constitutive. The resistance to β-lactam antibiotics is directly proportional to the number of copies of the bla gene and the enzyme synthesized. ...
Infect. Drug Rchesairsat.c1te4r,iz1a6t1io3n–1o6f2a2n. hotvteplsp:/l/adsomi.iodr-gb/o1r0n.2e1b4l7a/NIDDRM.S-2li9k7e4g1e9n(e2,0b2la1A).FM-1, in a clinical strain 21. Li, Y. et al. Genetic and virulence characteristics of a Raoultella plant...
Sub-optimal drug concentrations: does a lack of stability lead to inadequate beta-lactam time above the minimum inhibitory concentration (MIC)? The initial BLING RCT gave CI piperacillin/tazobactam or meropenem infusions as 100mL of diluent over back-to-back 8 h infusions and measured serum concen...
In this report, we used Xcc strain Xc17 as a model to study the role of the LysR box and the long-term induction effect of β-lactam in transcription of bla, as well as the extracellular secretion phenotype of β-lactamase. We find that intrinsic β−lactamase expression of Xanthomonas ...
Definitions of terms used to collect data Abbreviations ORs: Odds ratios; CI: Confidence intervals; UTI: Urinary tract infection; ICU: Intensive care unit; COPD: Chronic obstructive pulmonary disease; IVDU: Intravenous drug use; CDI: Clostridioides difficile infection; CA- UTI: Catheter-...
Background: Suspicion of beta-lactam (BL) hypersensitivity is often based on parental report. Evaluation is important as incorrect labelling has clinical consequence. Objective: To describe the outcomes of drug provocation test (DPT) in children with suspected hypersensitivity. Methods: A retrospective ...
BMC Infectious Diseases (2020) 20:57 https://doi.org/10.1186/s12879-020-4781-x STUDY PROTOCOL Open Access The effect of therapeutic drug monitoring of beta-lactam and fluoroquinolones on clinical outcome in critically ill patients: the DOLPHIN trial protocol of a multi-centre randomised controlled...