We used a Dirichlet-multinomial distribution to generate microbial OTU counts for each individual in the sample, as this distribution well accommodates the over-dispersion of microbiome count data [12, 70]. To ensure a realistic simulation of OTU counts, we estimated the parameters of the Dirichle...
proposed an omnibus test based on a zero-in- flated negative model (ZINB) that allows differential ana- lysis not only for feature abundance but also prevalence and dispersion [25]. However, the downside of these count-based methods is the increased complexity due to modeling the counts. ...
The present invention relates to, inter alia, safe and effective doses of a beta-lactamase for, e.g. microbiome protection.
(according to warming, nutrient enrich- ment, and different warming and nutrient treat- ments), the observed bacterioplankton communities all differed significantly from the null expectation, which included only stochastic community assem- bly processes (permutational analysis of multivariate dispersion: Po...
In respect to the latter point, it is noteworthy that “MMTV displays the most random dispersion of integration sites among retroviruses determined so far” [268].” Hence, two explanations are possible and deserve to be investigated: (1) Different strains of HRBV exist, and are able to acti...
We only investigated changes in the microbiome from the F0 generation between A1 and A2 fed mice and data on BCM-7 detection is limited to lymph nodes and blood. The major strength of this study is that experimental conditions were stringently controlled throughout and diabetes incidence across ...
(24.9 °C), dispersion medium viscosity (0.897 mPa·s), conductivity (0.264 mS/cm), and electrode voltage (3.3 V). The TEM analyses were run on a Thermoscientific Talos F200i (Waltham, MA, USA) using a carbon-coated grid (Type G 200, 3.05 µ diameter, TAAP, Seattle, DC, USA) ...
Zeta potential analyses were run on HORIBA SZ-100 (Singapore), with a holder (24.9 ◦C), dispersion medium viscosity (0.897 mPa·s), conductivity (0.264 mS/cm), and electrode voltage (3.3 V). The TEM analy- ses were run on a Thermoscientific Talos F200i (Waltham, MA, USA) using ...
Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure 2023, Cell Reports Medicine Citation Excerpt : While the beneficial effects of bariatric surgery were first attributed to the greatly reduced size of the stomach...